2375-03-3 Usage
Description
6alpha-Methylprednisolone sodium succinate, also known as 6alpha-methylprednisolone 21-hemisuccinate sodium salt, is a synthetic glucocorticoid derived from the corticosteroid class of drugs. It exhibits potent anti-inflammatory and immunosuppressive properties, making it a valuable compound in the medical field for various therapeutic applications.
Uses
Used in Pharmaceutical Industry:
6alpha-Methylprednisolone sodium succinate is used as an anti-inflammatory medication for the treatment of spinal cord injuries. Its potent anti-inflammatory action helps in reducing inflammation and promoting healing in such cases.
Used in Research and Development:
6alpha-Methylprednisolone sodium succinate is utilized in the investigation of glucocorticoid-induced osteonecrosis under hypoxic conditions. It is employed in various experimental setups, such as cell cytotoxicity assays, flow cytometry, and western blotting, to study its effects on the MC3T3-E1 osteoblast cell line.
Brand Names:
Some of the brand names under which 6alpha-Methylprednisolone sodium succinate is marketed include A-Methapred (Abbott), A-Methapred (Hospira), and Solu-Medrol (Pharmacia & Upjohn). These formulations are widely used in clinical settings for the treatment of various inflammatory and immunological conditions.
Biochem/physiol Actions
Glucocorticoid with slightly longer half-life than that of prednisolone.
Check Digit Verification of cas no
The CAS Registry Mumber 2375-03-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,7 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2375-03:
(6*2)+(5*3)+(4*7)+(3*5)+(2*0)+(1*3)=73
73 % 10 = 3
So 2375-03-3 is a valid CAS Registry Number.
InChI:InChI=1/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16?,17?,19-,23?,24-,25-,26-;/m0./s1