23755-78-4

Basic information

• Product Name: Phosphonic acid, (bromophenylmethyl)-, diethyl ester
• CAS NO: 23755-78-4
• Molecular Formula: C11H16BrO3P
• Molecular Weight: 307.124
• Mol File: 23755-78-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (bromophenylmethyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (bromophenylmethyl)-, diethyl ester(23755-78-4)
• EPA Substance Registry System: Phosphonic acid, (bromophenylmethyl)-, diethyl ester(23755-78-4)

Safety Data

• Hazardous Substances Data: 23755-78-4(Hazardous Substances Data)

Upstream product

• 1663-55-4 diethyl [hydroxy(phenyl)methyl]phosphonate 
• 791-28-6 Triphenylphosphine oxide 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 1972-28-7 diethylazodicarboxylate 
• 100-39-0 benzyl bromide 

Downstream Products

• 40962-35-4 [bromo(phenyl)methyl]phosphonic acid 

Relevant articles and documents

Quiescent affinity inactivators of protein tyrosine phosphatases

-Halobenzylphosphonates were investigated as possible inactivators of protein tyrosine phosphatases (PTPases). These compounds inactivate the Yersinia PTPase (Yop51*Δ162) in a time- and concentration-dependent fashion. This inactivation is active-site dir

The Iodine Atom Transfer Addition Reaction (I-ATRA) initiated by AIBN: Optimization, scope and radical reaction pathways

Optimization of reaction conditions (alkene, halide, solvent, stoichiometry, manners of the reagents addition, and reaction time) of the I-ATRA reactions involving 1-iodoalkylphosphonates was carried out. GC-MS-CI/EI analyses showed main and side products of this reaction and the corresponding radical reaction pathways leading to products derived from phosphorus and nonphosphorus containing iodides, as well as explained the source of hydrogen in radical reduction processes accompanying the I-ATRA reaction. Synthesis of some 3-iodoalkyl and 3-iodoalkenylphosphonates was also presented based on the optimized procedure.

Controlled monohalogenation of phosphonates: A new route to pure α- monohalogenated diethyl benzylphosphonates

Starting from diethyl benzylphosphonates, a wide variety of diethyl α- monofluoro, chloro, bromo and iodobenzylphosphonates have been obtained in pure form by a one-pot procedure. This high yielding method implies the intermediate protection of the benzyl anion with TMSCI followed by halogenation with an electrophilic halogenating reagent.