23827-93-2

Basic information

• Product Name: H-SER-PRO-OH
• Synonyms: L-SERYL-L-PROLINE;H-SER-PRO-OH;1-(L-Seryl)-L-proline;1-Serylproline;L-Ser-L-Pro-OH;Ser-Pro-OH;(S)-1-((S)-2-Amino-3-hydroxypropanoyl)pyrrolidine-2-carboxylic acid
• CAS NO: 23827-93-2
• Molecular Formula: C₈H₁₄N₂O₄
• Molecular Weight: 202.21
• Mol File: 23827-93-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 524.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.430±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.08±0.20(Predicted)
• CAS DataBase Reference: H-SER-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-SER-PRO-OH(23827-93-2)
• EPA Substance Registry System: H-SER-PRO-OH(23827-93-2)

Safety Data

• Hazardous Substances Data: 23827-93-2(Hazardous Substances Data)

Usage

General Description

H-SER-PRO-OH, also known as serine-proline, is a chemical compound consisting of the amino acids serine and proline. Amino acids are the building blocks of proteins and play a crucial role in various biological processes. Serine is a nonessential amino acid, meaning that it can be synthesized by the human body, and is involved in the synthesis of proteins, purines, and pyrimidines. Proline, on the other hand, is a unique amino acid that plays an important role in the structure and function of proteins. Together, serine and proline contribute to the formation of proteins and are essential for the proper functioning of the human body.

Upstream product

• 1239586-04-9 C₂₃H₂₄N₂O₆ 
• 2133-40-6 L-proline methyl ester monohydrochloride 
• 73724-45-5 N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine 

Downstream Products

• 23827-98-7 Z-Gly-L-Phe-Ser-Pro-OH 
• 73538-42-8 Gly-D-Phe-Ser-Pro 
• 23827-99-8 Gly-L-Phe-Ser-Pro 

Relevant articles and documents

Cyclo(l-proline-l-serine) Dipeptide Suppresses Seed Borne Fungal Pathogens of Rice: Altered Cellular Membrane Integrity of Fungal Hyphae and Seed Quality Benefits

Five proline-containing diketopiperazines (Pro-DKPs) produced by antagonistic microorganisms as secondary metabolites were selected and synthesized under laboratory conditions. Out of five synthesized Pro-DKPs, cyclo(l-Pro-l-Ser) (DKP-6) revealed the best inhibition of fungal pathogens (Fusarium verticillioides and Fusarium fujikuroi) of rice under in vitro conditions with effective doses lower than standard fungicide carbendazim. DKP-6 induced stress on the fungal cell membrane integrity, which was revealed by calcofluor white and propidium iodide assays, endorsed by ultra-microscopic details and soluble protein leakage assays. In vivo seed treatment of infested rice seeds with DKP-6 at 2000 μg/mL for 10 h of seed treatment inflicted best reduction in seed rot and seedling blight with respect to control and carbendazim. Significant enhancement in seedling quality parameters were also observed. The work presented the strong influence of cyclo(l-Pro-l-Ser) as a mycocidal seed treatment agent better than synthetic toxic fungicides for rice.