23834-01-7

Basic information

• Product Name: 4,5,7-Trichloro Quinoline
• Synonyms: 4,5,7-Trichloro Quinoline;BUTTPARK 177\09-89
• CAS NO: 23834-01-7
• Molecular Formula: C₉H₄Cl₃N
• Molecular Weight: 232.49376
• EINECS: 1533716-785-6
• Mol File: 23834-01-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 327oC
• Flash Point: 181.2oC
• Appearance: Type white crystalline powders
• Density: 1.523±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.000405mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Sparingly), Toluene (Slightly, Sonicated)
• CAS DataBase Reference: 4,5,7-Trichloro Quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,7-Trichloro Quinoline(23834-01-7)
• EPA Substance Registry System: 4,5,7-Trichloro Quinoline(23834-01-7)

Safety Data

• Hazard Codes: T
• Statements: 25-41
• Safety Statements: 26-39-45
• Hazardous Substances Data: 23834-01-7(Hazardous Substances Data)

Usage

Description

4,5,7-Trichloro Quinoline is an organic compound with the molecular formula C9H5Cl3N2. It is a derivative of quinoline, a tricyclic aromatic compound, and is characterized by the presence of three chlorine atoms at the 4, 5, and 7 positions. 4,5,7-Trichloro Quinoline is known for its chemical properties and potential applications in various industries.

Uses

Used in Agricultural Industry:
4,5,7-Trichloro Quinoline is used as an intermediate in the synthesis of Quinoxyfen-d4 (Q765502), an isotope-labelled version of Quinoxyfen. Quinoxyfen is an agricultural fungicide that helps protect crops from fungal infections, ensuring better yield and quality of the produce.
In the synthesis process, 4,5,7-Trichloro Quinoline serves as a crucial building block for the creation of the isotope-labelled compound, which can be used for various purposes, such as studying the mechanism of action of the fungicide or for tracking its movement and distribution in the environment. This application highlights the importance of 4,5,7-Trichloro Quinoline in the development of effective and environmentally friendly agricultural solutions.

InChI:InChI=1/C9H4Cl3N/c10-5-3-7(12)9-6(11)1-2-13-8(9)4-5/h1-4H

Upstream product

• 171850-29-6 4-hydroxy-5,7-dichloroquinoline 
• 626-43-7 3,5-Dichloroaniline 
• 131123-76-7 5,7-dichlorokynurenic acid 
• 157848-08-3 5,7-dichloro-4-hydroxy-quinoline-2-carboxylic acid ethyl ester 
• 33149-04-1 β-(3,5-dichloroanilino)propionitrile 

Downstream Products

• 5437-27-4 N⁴,N⁴-diethyl-N¹-(5,7-dichloro-[4]quinolyl)-1-methyl-butanediyldiamine 
• 124495-18-7 5,7-dichloro-4-(4-fluorophenoxy)quinoline 

Relevant articles and documents

4. The preparation method of the 5, 7 - trichloro quinoline (by machine translation)

The invention discloses 4, 5, 7 - trichloro quinoline of the preparation method, it [...] shown (I) 5, 7 - dichloro - 2, 3 - dihydro-quinoline - 4 (1 H) - one dissolved in reagent chloride and 1st in the organic solvent, at a temperature of 80 - 120 °C reaction under 10 - 17 h, after the reaction, the reaction liquid is post-processed to obtain the formula (II) as shown in the 4, 5, 7 - trichloro quinoline; reaction as follows: . The invention through one-step will be 5, 7 - dichloro - 2, 3 - dihydro-quinoline - 4 (1 H) - one obtained by synthesizing 4, 5, 7 - trichloro quinoline, this method has the advantages of simple, efficient, yield and low cost. (by machine translation)

Process to produce halo-4-phenoxyquinolines

The present invention relates to a process for the preparation of halo-4-phenoxyquinolines.

Catalytic enantioselective reissert-type reaction: Development and application to the synthesis of a potent NMDA receptor antagonist (-)-L-689,560 using a solid-supported catalyst

Full details of the first catalytic enantioselective Reissert-type reaction are described. Utilizing the Lewis acid-Lewis base bifunctional catalyst 5 or 6 (9 mol %), the Reissert products were obtained in 57 to 99% yield with 54 to 96% ee. Electron-rich