23876-13-3

Basic information

• Product Name: 2-Methyl-3-nitrobenzyl alcohol
• Synonyms: 2-METHYL-3-NITROBENZYL ALCOHOL;2-Methyl-3-Nitrobenzyl;2-Methyl-3-nitrobenzyl alcohol 98%;Benzenemethanol, 2-methyl-3-nitro-;2-Methyl-3-nitrobenzyl alcohol,99%;Einecs 245-923-1;(2-Methyl-3-nitrophenyl)Methanol
• CAS NO: 23876-13-3
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• EINECS: 245-923-1
• Product Categories: Alcohol Aldehyde & acid series;Alcohols;C7 to C8;Oxygen Compounds
• Mol File: 23876-13-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: 69-73 °C(lit.)
• Boiling Point: 323.2 °C at 760 mmHg
• Flash Point: 145.5 °C
• Appearance: white to light yellow crystal powder
• Density: 1.272 g/cm³
• Vapor Pressure: 0.000109mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.83±0.10(Predicted)
• CAS DataBase Reference: 2-Methyl-3-nitrobenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-3-nitrobenzyl alcohol(23876-13-3)
• EPA Substance Registry System: 2-Methyl-3-nitrobenzyl alcohol(23876-13-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 23876-13-3(Hazardous Substances Data)

Usage

Description

2-Methyl-3-nitrobenzyl alcohol is an organic compound characterized by its white to light yellow crystalline powder form. It is known for its distinct chemical structure, which features a methyl group at the 2nd position and a nitro group at the 3rd position on a benzyl alcohol backbone.

Uses

Used in Chemical Synthesis:
2-Methyl-3-nitrobenzyl alcohol is used as a key intermediate in the chemical synthesis of various compounds. Its unique structure allows it to be a versatile building block for creating a range of molecules with different applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methyl-3-nitrobenzyl alcohol is used as a starting material for the synthesis of pharmaceutical compounds. Its reactivity and structural features make it a valuable component in the development of new drugs.
Used in Chemical Research:
2-Methyl-3-nitrobenzyl alcohol is also utilized in chemical research as a model compound to study various reaction mechanisms and to understand the properties of similar organic molecules.
Used in the Synthesis of 2-Methyl-3-nitrobenzyl Cyanide:
2-Methyl-3-nitrobenzyl alcohol is used as a precursor in the preparation of 2-methyl-3-nitrobenzyl cyanide, which is an important compound in the chemical industry with various applications.
Used in the Synthesis of 20-Membered Macrocyclic Thiodepsipeptide:
Furthermore, 2-Methyl-3-nitrobenzyl alcohol is employed in the synthesis of 20-membered macrocyclic thiodepsipeptides, which are complex molecules with potential applications in various fields, including pharmaceuticals and materials science.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

InChI:InChI=1/C8H9NO3/c1-6-7(5-10)3-2-4-8(6)9(11)12/h2-4,10H,5H2,1H3

Upstream product

• 83647-42-1 3-amino-2-methylbenzyl alcohol 
• 1975-50-4 2-methyl-3-nitrobenzic acid 
• 23876-12-2 3-formyl-2-methyl-1-nitrobenzene 
• 39053-41-3 2-methyl-3-nitrobenzoyl chloride 
• 7647-01-0 hydrogenchloride 
• 89929-95-3 2-methyl-3-nitrophenylmethyl acetate 
• 59383-08-3 2-methyl-3-nitro-thiobenzoic acid S-benzyl ester 
• 71516-35-3 2-methyl-3-nitrobenzonitrile 
• 83-41-0 2,3-dimethylnitrobenzene 
• 23876-11-1 2-methyl-3-nitrobenzol-1-methandiol diacetate 
• 59382-59-1 2-methyl-3-nitro-benzoic acid methyl ester 

Downstream Products

• 60468-54-4 1-chloromethyl-2-methyl-3-nitro-benzene 
• 23876-14-4 3-nitro-2-methylphenylacetonitrile 
• 89929-99-7 6-nitro-2-(2-tetrahydropyranyloxy)methyltoluene 
• 177326-60-2 2-(methoxyethoxymethyloxy)methyl-6-nitrotoluene 
• 196500-09-1 2-methyl-3-nitrobenzyl methanesulfonate 
• 23876-12-2 3-formyl-2-methyl-1-nitrobenzene 
• 39053-40-2 1-(bromomethyl)-2-methyl-3-nitrobenzene 
• 912819-07-9 trimethyl(2-{[(2-methyl-3-nitrobenzyl)oxy]methoxy}ethyl)silane 
• 912819-09-1 methyl 3-[2-nitro-({[2-(trimethylsilyl)ethoxy]methoxy}methyl)phenyl]-2-oxopropanoate 
• 912819-13-7 methyl 3-[2-nitro-6-({[2-(trimethylsilyl)ethoxy]methoxy}methyl)phenyl]-2-oxobut-3-enoate 
• 928128-09-0 methyl 3-amino-2-methylbenzenepropanoate 
• 928128-08-9 methyl 2-methyl-3-nitrobenzenepropanoate 
• 928128-06-7 methyl 2-methyl-3-(methylamino)benzenepropanoate 
• 928128-07-8 dimethyl 2-[(2-methyl-3-nitrophenyl)methyl]propanedionate 

Relevant articles and documents

Combined production method for substituted benzaldehyde, substituted benzyl alcohol and substituted benzoic acid

The invention discloses a combined production method for substituted benzaldehyde, substituted benzyl alcohol and substituted benzoic acid. The method comprises the following steps: (1) oxidation: a step of continuously introducing substituted toluene, a catalyst and oxygen-contained gas into an oxidation reactor and carrying out reaction so as to obtain oxidation reaction liquid; (2) hydrolyzation: a step of allowing the oxidation reaction liquid to continuously enter a hydrolysis reactor, and continuously adding water into the hydrolysis reactor and carrying out reaction so as to obtain a hydrolysis reaction mixture; (3) liquid-liquid layering: a step of layering the hydrolysis reaction mixture so as to obtain an oil phase and an aqueous phase; and (4) separation of products: a step of subjecting the oil phase to distillation so as to respectively obtain incompletely-reacted substituted toluene, substituted benzyl alcohol and substituted benzaldehyde, and subjecting the aqueous phase to cooling, crystallizing and filtering so as to obtain filtrate and substituted benzoic acid. The combined production method provided by the invention has the advantages of high raw material conversion rate, few by-products, good selectivity of target products, greenness and environmental protection.

TETRAZOLINONE COMPOUND AND USE THEREOF

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.

TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES

The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, or a C3-C12 cycloalkyl group, etc., which each optionally be substituted; R2, R3, R4 and R5 represent independently of each other a hydrogen atom, a halogen atom or an C1-C3 alkyl group, etc.; R6 represents an C1-C6 alkyl group, a C3-C6 cycloalkyl group, a halogen atom, a C1-C6 haloalkyl group, an C2-C6 alkenyl group, an C1-C6 alkoxy group, or a C1-C6 haloalkoxy group, etc.; R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, or an C1-C4 alkyl group, etc.; X represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.