23949-31-7

Basic information

• Product Name: 1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran
• Synonyms: 1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran
• CAS NO: 23949-31-7
• Molecular Weight: 256.301
• Mol File: 23949-31-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran(23949-31-7)
• EPA Substance Registry System: 1-(2,4-dimethoxy-phenyl)-1,3-dihydro-isobenzofuran(23949-31-7)

Safety Data

• Hazardous Substances Data: 23949-31-7(Hazardous Substances Data)

Upstream product

• 496-14-0 1,3-dihydroisobenzofuran 
• 151-10-0 1,3-Dimethoxybenzene 

Relevant articles and documents

Gold-catalyzed benzylic azidation of phthalans and isochromans and subsequent FeCl3-catalyzed nucleophilic substitutions

The benzylic positions of the phthalan and isochroman derivatives (1) as benzene-fused cyclic ethers effectively underwent gold-catalyzed direct azidation using trimethylsilylazide (TMSN3) to give the corresponding 1-azidated products (2) possessing the N,O-acetal partial structure. The azido group of the N,O-acetal behaved as a leaving group in the presence of catalytic iron(III) chloride, and 1-aryl or allyl phthalan and isochroman derivatives were obtained by nucleophilic arylation or allylation, respectively. Meanwhile, a double nucleophilic substitution toward the 1-azidated products (2) occurred at the 1-position using indole derivatives as a nucleophile accompanied by elimination of the azido group and subsequent ring opening of the cyclic ether nucleus produced the bisindolylarylmethane derivatives.