24006-92-6

Basic information

• Product Name: 4,5-DICHLORO-1,2-BENZENEDIMETHANOL
• Synonyms: 4,5-DICHLORO-1,2-BENZENEDIMETHANOL;AKOS 92358;(4,5-Dichloro-1,2-phenylene)dimethanol
• CAS NO: 24006-92-6
• Molecular Formula: C₈H₈Cl₂O₂
• Molecular Weight: 207.05
• Mol File: 24006-92-6.mol
• Article Data: 21

Chemical Properties

• Melting Point: 137-139 °C
• Boiling Point: 349.832 °C at 760 mmHg
• Flash Point: 165.373 °C
• Appearance: /
• Density: 1.468 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.30±0.10(Predicted)
• CAS DataBase Reference: 4,5-DICHLORO-1,2-BENZENEDIMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DICHLORO-1,2-BENZENEDIMETHANOL(24006-92-6)
• EPA Substance Registry System: 4,5-DICHLORO-1,2-BENZENEDIMETHANOL(24006-92-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 24006-92-6(Hazardous Substances Data)

Usage

General Description

4,5-Dichloro-1,2-benzenedimethanol is a chemical compound with the molecular formula C8H8Cl2O2. It is a white crystalline solid that is used in the production of pharmaceuticals, agrochemicals, and other organic compounds. It has antimicrobial properties and is often used as a preservative in cosmetic and personal care products. The compound is synthesized through the chlorination of 1,2-benzenedimethanol, resulting in the substitution of chlorine atoms at the 4 and 5 positions on the benzene ring. 4,5-Dichloro-1,2-benzenedimethanol is considered to be moderately toxic and should be handled with care and in accordance with safety precautions.

InChI:InChI=1/C8H8Cl2O2/c9-7-1-5(3-11)6(4-12)2-8(7)10/h1-2,11-12H,3-4H2

Upstream product

• 942-06-3 4,5-dichlorophthalic anhydride 
• 56962-08-4 4,5-dichlorophthalic acid 
• 106727-86-0 4,5-dichlorophthalic acid dimethyl ester 

Downstream Products

• 21903-56-0 1,2-bis(bromomethyl)-4,5-dichlorobenzene 
• 13209-33-1 4,5-dichlorobenzene-1,2-dicarbaldehyde 
• 34588-40-4 2,3,6,7-tetrachloronaphthalene 
• 130217-38-8 2-(((tert-butyldimethylsilyl)oxy)methyl)-4,5-dichlorobenzaldehyde 
• 130217-40-2 [1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-4,5-dichloro-phenyl]-meth-(E)-ylidene]-trimethylsilanylmethyl-amine 
• 130217-45-7 Dimethyl 2,5-Dihydro-1-benzyloxycarbonyl-2-(2-chloromethyl-4,5-dichlorophenyl)pyrrole-3,4-dicarboxylate 
• 130217-42-4 Dimethyl 2,5-Dihydro-1-benzyloxycarbonyl-2-<2-(t-butyldimethylsilyloxymethyl)-4,5-dichlorophenyl>pyrrole-3,4-dicarboxylate 
• 872181-18-5 (4,5-dichloro-2-methoxymethoxymethylphenyl)methanol 
• 280134-99-8 4-formyl-1-(4,5-dichloro-2-hydroxymethylbenzyl)-indole 
• 1316054-11-1 (E)-4,5-dichloro-2-[(2-hydroxy-3-nitrocyclohex-2-en-1-yliden)methyl]benzaldehyde 
• 1379772-67-4 (6,7-dichloro-3-phenylnaphthalen-2-yloxy)triisopropylsilane 
• 24006-91-5 5,6-dichloroisobenzofuran-1(3H)-one 
• 1092446-91-7 2-(2-cyclobutyloxy-3-methyl-benzoylamino)-5,6-dichloro-indan-2-carboxylic acid 
• 1092448-42-4 2-(2-cyclobutyloxy-3-methyl-benzoylamino)-5,6-dichloro-indan-2-carboxylic acid ethyl ester 

Relevant articles and documents

2,3-Dihalo- and 2,3,6,7-Tetrahaloanthracenes by Vollhardt Trimerization

We efficiently synthesized otherwise difficult to obtain 2,3- and 2,3,6,7-halogenated anthracenes with diverse east/west substituents. Key steps involve the (i) Vollhardt cyclization of bis(propargyl)benzenes with bis(trimethylsilyl)acetylene, (ii) halo-desilylation introducing chlorine, bromine, or iodine substituents, and (iii) dehydrogenation. Pd catalysis allows selective functionalization at the anthracenes' east/west positions. A tetrahydropentacene is synthesized and derivatized via the same strategy, employing tetrapropargylbenzene.

Synthesis and optoelectronic properties of hexachloro- and hexaiodosubnaphthalocyanines as organic electronic materials

Chloroboron(III) hexachloro- and hexaiodosubnaphthalocyanines were prepared, and their solubility, electronic absorption spectroscopy, fluorescence emission spectroscopy and HOMO/LUMO energy levels were evaluated. These subnaphthalocyanines showed lower H

Iron(II) pincer-catalyzed synthesis of lactones and lactams through a versatile dehydrogenative domino sequence

The synthesis of lactones and lactams by using iron(II) pincer-catalyzed dehydrogenative methodology was developed. Starting from 1,n-diols or 1,n-amino alcohols, this domino transformation takes place through initial dehydrogenation of the substrates, subsequent intramolecular cyclization, and final oxidation to afford the desired products in good yields. The ability to access heterocycles of different sizes makes this protocol especially versatile, in which two consecutive oxidation reactions are performed without requiring an external oxidant. In this paper, we report the application of the Fe-MACHO-BH complex [carbonylhydrido(tetrahydroborato)[bis(2-diisopropylphosphinoethyl)amino]iron(II)] in this atom-efficient and environmentally benign process, for which molecular hydrogen is formed as the only stoichiometric side product. Just a little pinch: The iron(II) pincer-catalyzed synthesis of lactones and lactams from easily available 1,n-diols and 1,n-amino alcohols is explored. The use of a nontoxic metal as well as the generation of molecular hydrogen as the only stoichiometric byproduct makes this method a highly atom-efficient and environmentally benign process.