24117-97-3

Basic information

• Product Name: benzyl N-[(benzyloxy)carbonyl]glycylphenylalaninate
• CAS NO: 24117-97-3
• Molecular Formula: C₂₆H₂₆N₂O₅
• Molecular Weight: 446.495
• Mol File: 24117-97-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 671.7°C at 760 mmHg
• Flash Point: 360°C
• Density: 1.224g/cm³
• Vapor Pressure: 6.68E-18mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: benzyl N-[(benzyloxy)carbonyl]glycylphenylalaninate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N-[(benzyloxy)carbonyl]glycylphenylalaninate(24117-97-3)
• EPA Substance Registry System: benzyl N-[(benzyloxy)carbonyl]glycylphenylalaninate(24117-97-3)

Safety Data

• Hazardous Substances Data: 24117-97-3(Hazardous Substances Data)

Upstream product

• 15050-24-5 N-(benzyloxycarbonyl)glycyl chloride 
• 6443-91-0 ethynyl methyl ether 
• 962-39-0 L-Phenylalanine benzyl ester 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 1738-78-9 L-phenylalanine benzyl ester p-toluene-sulfonic acid salt 
• 24080-16-8 O--cyclopentanon-oxim 
• 2462-32-0 L-phenylalanine benzyl ester hydrochloride 
• 1170-76-9 Z-Gly-(L)-Phe 

Downstream Products

• 3321-03-7 Gly-Phe-OH 
• 87004-75-9 N-glycyl-L-phenylalanine benzyl ester; hydrobromide 
• 2073-59-8 ethyl N-benzyloxycarbonylglycyl-L-phenylalanylglycinate 
• 34095-05-1 N-benzyloxycarbonyl-glycyl=>glycyl=>phenylalanine benzyl ester; N-benzyloxycarbonyl-glycyl=>glycyl=>L-phenylalanine benzyl ester 

Relevant articles and documents

Peptide Synthesis in Aqueous Solution. V. Properties and Reactivities of (p-Hydroxyphenyl)benzylmethylsulfonium Salts for Direct Benzyl Esterification of N-Acylpeptides

Some (p-hydroxyphenyl)benzylmethylsulfonium salts were prepared. These compounds generated a benzyl cation and converted not only N-acylamino acids but also N-acylpeptides into their corresponding benzyl esters without causing the racemization.

A CONVENIENT METHOD FOR THE SYNTHESIS OF CARBOXAMIDES AND PEPTIDES BY THE USE OF TETRABUTYLAMMONIUM SALTS

Various carboxamides and peptides are prepared in good yields by treatment of free acids and amines in H2O-dichloromethane or aqueous THF with bis(o-nitrophenyl) phenylphosphonate in the presence of tetrabutylammonium hydrogen sulfate or bromide.Carboxylic esters are also successfully converted to amides via carboxylate salts in one-pot.