24182-11-4 Usage
General Description
(R)-PIPERAZINE-2-CARBOXYLIC ACID is a chemical compound with the molecular formula C6H10N2O2. It is a derivative of piperazine, a heterocyclic amine. (R)-PIPERAZINE-2-CARBOXYLIC ACID is used as an intermediate in the synthesis of various pharmaceuticals and research chemicals. It is also used as a building block in the production of active pharmaceutical ingredients. (R)-PIPERAZINE-2-CARBOXYLIC ACID is a chiral compound, meaning it has two enantiomers, and the (R)-enantiomer is the biologically active form. This chemical is an important component in drug discovery and development, particularly in the production of drugs for central nervous system disorders and cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 24182-11-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,8 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 24182-11:
(7*2)+(6*4)+(5*1)+(4*8)+(3*2)+(2*1)+(1*1)=84
84 % 10 = 4
So 24182-11-4 is a valid CAS Registry Number.
24182-11-4Relevant articles and documents
Synthesis of cyclic α-hydrazino acids
Duttagupta, Indranil,Goswami, Koushik,Sinha, Surajit
experimental part, p. 8347 - 8357 (2012/09/21)
Synthesis of five-, six-, seven-, eight-, and nine-membered cyclic α-hydrazino acids from a common starting material 'diethylmalonate' with 26, 16, 34, 13.5, and 13.33% overall yields is described. Sequential allylation or homoallylation and electrophilic amination followed by cyclization gave the desired rings. The methyl esters of eight- and nine-membered rings were synthesized by RCM and the corresponding free acids were generated after hydrolysis in the presence of 1 M BBr3 solution in DCM.
An alternative convenient synthesis of piperidazine-3-carboxylic acid derivatives
Kaname, Mamoru,Yamada, Masae,Yoshifuji, Shigeyuki,Sashida, Haruki
experimental part, p. 49 - 54 (2009/07/25)
The short-step synthesis of the unsubstituted, 5-hydroxy- and 5-chloropiperidazine-3-carboxylic acids using an aza Diels-Alder reaction between the 1,3-diene and azodicarboxylate was described. This synthetic methodology could be used for the preparation