24211-53-8Relevant articles and documents
Concise Enantioselective Synthesis of Naturally Active (S)-3-Hydroxypiperidine
Dey, Soumen,Karabal, Pratibha U.,Sudalai, Arumugam
, p. 1559 - 1565 (2015/06/02)
A short and efficient enantioselective synthesis of natural product (S)-3-hydroxypiperidine has been achieved starting from commercially available raw materials employing two catalytic routes: (i) cocatalyzed hydrolytic kinetic resolution (HKR) of racemic methyl-3-(oxiran-2-yl)propanoate; (ii) proline-catalyzed α-aminooxylation followed by Horner-Wardsworth-Emmons olefination in high enantiomeric purity (97% ee) and high overall yield (38%). (Chemical Equation Presented).
Syntheses of (S)-(-)-3-Piperidinol from L-Glutamic Acid and (S)-Malic Acid
Olsen, Richard K.,Bhat, Krishna L.,Wardle, Robert B.,Hennen, William J.,Kini, Ganesh D.
, p. 896 - 899 (2007/10/02)
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