24242-77-1

Basic information

• Product Name: Ethanone, 2-iodo-1,2-diphenyl-
• CAS NO: 24242-77-1
• Molecular Formula: C14H11IO
• Molecular Weight: 322.145
• Mol File: 24242-77-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-iodo-1,2-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-iodo-1,2-diphenyl-(24242-77-1)
• EPA Substance Registry System: Ethanone, 2-iodo-1,2-diphenyl-(24242-77-1)

Safety Data

• Hazardous Substances Data: 24242-77-1(Hazardous Substances Data)

Upstream product

• 501-65-5 diphenyl acetylene 
• 451-40-1 phenyl benzyl ketone 
• 1484-50-0 desyl bromide 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 67-56-1 methanol 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 26226-48-2 1,2-diphenyl-1-nitrooxirane 
• 447-31-4 Desyl chloride 

Downstream Products

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 29864-19-5 2-(2-nitrophenyl)-4,5-diphenylimidazole 
• 1728-95-6 2-(4-methoxy-phenyl)-4,5-diphenyl-1H-imidazole 
• 2284-96-0 2-(4-fluorophenyl)-4,5-diphenyl-1H-imidazole 
• 14359-34-3 3-(4,5-diphenyl-1H-imidazol-2-yl)-1H-indole 
• 29916-33-4 2-(furan-2-yl)-4,5-diphenyl-1H-imidazole 
• 13866-85-8 2‐(naphthalen‐2‐yl)‐4,5‐diphenyl‐1H‐imidazole 
• 1740-26-7 2-(2-fluorophenyl)-4,5-diphenyl-1H-imidazole 
• 1965-19-1 2-(2-methoxyphenyl)-4,5-diphenyl-1H-imidazole 
• 5496-38-8 2-(3-nitrophenyl)-4,5-diphenyl-1H-imidazole 
• 134-81-6 benzil 
• 5496-31-1 2-(4-methylphenyl)-4,5-diphenyl-1H-imidazole 
• 5496-33-3 2-(4-bromophenyl)-4,5-diphenyl-1H-imidazole 
• 5496-32-2 2-(4-chlorophenyl)-4,5-diphenyl-1H-imidazole 

Relevant articles and documents

Molecular iodine/DMSO mediated oxidation of internal alkynes and primary alcohols using a one-pot, two step approach towards 2,4,5-trisubstituted imidazoles: Substrate scope and mechanistic studies

An efficient, eco-friendly and practical oxidation of internal alkynes and primary alcohols as key steps towards the synthesis of 2,4,5-trisubstituted imidazoles is reported. This green synthetic methodology employed an acid and metal-free molecular iodine/DMSO system, to afford a variety of substituted imidazoles in moderate to good yields, with a range of functionalities tolerated. Mechanistic studies revealed two distinct oxidation pathways, which ultimately form the diketone and aldehyde that serve as key intermediates in the multicomponent domino synthesis.

Iodine/DMSO promoted oxidation of benzylic Csp3–H bonds to diketones – A mechanistic investigation

This article describes a mechanistic investigation into the I2/DMSO mediated benzylic Csp3–H oxidation of an α-methylene ketone. The electron paramagnetic resonance (EPR) spectrum centred at g = 2.0011 supports the involvement of iodine and benzylic radicals, as the α-iodinated compound 2-iodo-1,2-diphenylethanone was isolated as a key reactive intermediate. The oxidation reaction relies, primarily, on DMSO as a source of oxygen in benzil, proven by the reaction of benzyl phenyl ketone with diphenyl sulfoxide (DPSO).

Iodination of alcohols over Keggin-type heteropoly compounds: A simple, selective and expedient method for the synthesis of alkyl iodides

Different catalysts derived from Keggin-type heteropoly compounds were prepared and their catalytic activities have been compared in the iodination of benzyl alcohol with KI under mild reaction conditions. A high catalytic activity was found over tungstophosphoric acid supported on silica and titania. The effect of catalyst loading, iodine source and the nature of substituents on the aromatic ring of benzyl alcohol were investigated. Finally, several competitive reactions were studied between structurally diverse alcohols. This protocol provides a mild and expedient way for the conversion of various alcohols to their corresponding alkyl iodides with high selectivity.