24282-61-9

Basic information

• Product Name: 1(3H)-Isobenzofuranone, 7-hydroxy-5-methoxy-4-methyl-
• CAS NO: 24282-61-9
• Molecular Formula: C10H10O4
• Molecular Weight: 194.187
• Mol File: 24282-61-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1(3H)-Isobenzofuranone, 7-hydroxy-5-methoxy-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(3H)-Isobenzofuranone, 7-hydroxy-5-methoxy-4-methyl-(24282-61-9)
• EPA Substance Registry System: 1(3H)-Isobenzofuranone, 7-hydroxy-5-methoxy-4-methyl-(24282-61-9)

Safety Data

• Hazardous Substances Data: 24282-61-9(Hazardous Substances Data)

Upstream product

• 188291-73-8 7-hydroxy-6-iodo-5-methoxy-4-methylisobenzofuran-1(3H)-one 
• 57061-31-1 3-benzenesulfinyl-5H-furan-2-one 
• 126393-67-7 1,3-dimethoxy-1-trimethylsilyloxy-1,3-pentadiene 

Downstream Products

• 24280-93-1 mycophenolic acid 
• 24243-40-1 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid methyl ester 
• 24280-93-1 mycophenolic acid 
• 31858-66-9 methyl mycophenolate 
• 27979-57-3 5,7-dihydroxy-4-methylphthalide 

Relevant articles and documents

Diels-Alder and Stille Coupling Approach for the Short Protecting-Group-Free Synthesis of Mycophenolic Acid, Its Phenylsulfenyl and Phenylselenyl Analogues, and Reactive Oxygen Species (ROS) Probing Capacity in Water

A short, protecting-group-free synthesis is achieved. The synthesis is step-efficient and general. A Diels-Alder and Stille cross-coupling approach includes key transformations, allowing for a competitive synthesis which involves a rare halophenol Stille cross-coupling study. The phenylselenyl and phenylsulfenyl analogues were prepared as novel compounds in good overall yield. The applicability of one of the intermediates as a potential probe for reactive oxygen species (ROS) in water is investigated.