24317-95-1

Basic information

• Product Name: Ethyl 2-acetyldecanoate
• Synonyms: ETHYL 2-OCTYLACETOACETATE;ethyl 2-acetyldecanoate;2-Acetyldecanoic acid ethyl ester;Einecs 246-158-6
• CAS NO: 24317-95-1
• Molecular Formula: C₁₄H₂₆O₃
• Molecular Weight: 242.35
• EINECS: 246-158-6
• Mol File: 24317-95-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 279.8 °C at 760 mmHg
• Flash Point: 113.5 °C
• Appearance: /
• Density: 0.929 g/cm³
• Vapor Pressure: 0.00393mmHg at 25°C
• Refractive Index: 1.439
• CAS DataBase Reference: Ethyl 2-acetyldecanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-acetyldecanoate(24317-95-1)
• EPA Substance Registry System: Ethyl 2-acetyldecanoate(24317-95-1)

Safety Data

• Hazardous Substances Data: 24317-95-1(Hazardous Substances Data)

Usage

General Description

Ethyl 2-acetyldecanoate is a chemical compound with the molecular formula C14H26O3. It is an ester, specifically a derivative of acetyldecanoic acid, and has a fruity, sweet aroma. Ethyl 2-acetyldecanoate is commonly used in the production of various flavors and fragrances, as well as in the food and beverage industry. It is also used as a solvent in some industrial processes. Ethyl 2-acetyldecanoate has been studied for its potential antimicrobial properties and is considered to be a low toxic substance with no known harmful effects on human health. Overall, it is a versatile chemical with a wide range of applications in different industries.

InChI:InChI=1/C14H26O3/c1-4-6-7-8-9-10-11-13(12(3)15)14(16)17-5-2/h13H,4-11H2,1-3H3

Upstream product

• 629-27-6 1-Iodooctane 
• 141-52-6 sodium ethanolate 
• 141-97-9 ethyl acetoacetate 
• 111-83-1 1-bromo-octane 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 111-66-0 oct-1-ene 
• 680859-92-1 2-acetyl-2-bromodecanoic acid ethyl ester 
• 71-48-7 cobalt(II) acetate 
• 638-38-0 manganese(II) acetate 
• 6186-89-6 ethyl methyl malonate 
• 623-73-4 diazoacetic acid ethyl ester 
• 693-54-9 Decan-2-one 

Downstream Products

• 112-12-9 methyl nonyl ketone 
• 19009-56-4 2-methyldecanal 
• 334-48-5 1-decanoic acid 
• 124-38-9 carbon dioxide 
• 6974-85-2 ethyl 2-bromodecanoate 

Relevant articles and documents

Synthetic Scope of Br?nsted Acid-Catalyzed Reactions of Carbonyl Compounds and Ethyl Diazoacetate

The comprehensive study of the reactions of carbonyl compounds and ethyl diazoacetate in the presence of a Br?nsted acid catalyst is described. In result, a broad range of 3-oxo-esters were synthesized from a variety of ketones and aliphatic aldehydes by 1,2-aryl/alkyl/hydride shift. Aryl-methyl ketones produced only aryl-migrated products, whereas other ketones yielded a mixture of products. For diaryl ketones, the identity of two inseparable migrated products was confirmed by two-dimensional NMR spectroscopy.

gem-Difluoroolefination of Diazo Compounds with TMSCF3 or TMSCF2Br: Transition-Metal-Free Cross-Coupling of Two Carbene Precursors

A new olefination protocol for transition-metal-free cross-coupling of two carbene fragments arising from two different sources, namely, a nonfluorinated carbene fragment resulting from a diazo compound and a difluorocarbene fragment derived from Ruppert-Prakash reagent (TMSCF3) or TMSCF2Br, has been developed. This gem-difluoroolefination proceeds through the direct nucleophilic addition of diazo compounds to difluorocarbene followed by elimination of N2. Compared to previously reported Cu-catalyzed gem-difluoroolefination of diazo compounds with TMSCF3, which possesses a narrow substrate scope due to a demanding requirement on the reactivity of diazo compounds and in-situ-generated CuCF3, this transition-metal-free protocol affords a general and efficient approach to various disubstituted 1,1-difluoroalkenes, including difluoroacrylates, diaryldifluoroolefins, as well as arylalkyldifluoroolefins. In view of the ready availability of diazo compounds and difluorocarbene reagents and versatile transformations of 1,1-difluoroalkenes, this new gem-difluoroolefination method is expected to find wide applications in organic synthesis.

A new diversity oriented and metal-free approach to highly functionalized 3H-pyrimidin-4-ones

A new synthesis of 3H-pyrimidin-4-ones, characterized by four different sets of decorations, is presented. The strategy is based on the synthetic elaboration of readily available α-substituted β-ketoesters that, upon transformation into the corresponding acyl enamines, have been cyclized to give 6H-1,3-oxazin-6-ones. These reactive intermediates have been in turn cleanly converted into highly functionalized pyirimidinones, by treatment with an appropriate primary amine. The whole sequence does not need the use of any metal mediator or catalyst.