244-50-8Relevant articles and documents
α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
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, (2008/06/13)
Cognitive defeciencies or neurological dysfunction in mammals are treated with α,α-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: STR1 or a salt thereof wherein X and Y are taken together to form a saturated or unsaturated carbocyclic or heterocyclic first ring and the shown carbon in said ring is α to at least one additional aromatic ring or heteroaromatic ring fused to the first ring; one of Het1 is 2, 3 or 4-pyridyl or 2, 4, or 5-pyrimidinyl and the other is selected from (a) 2, 3, or 4-pyridyl, (b) 2, 4, or 5-pyrimidinyl, (c) 2-pyrazinyl, (d) 3, or 4-pyridazinyl, (e) 3, or 4-pyrazolyl, (f) 2, or 3-tetrahydrofuranyl, and (g) 3-thienyl.
REACTIONS OF AZAFLUORENONES WITH HYDRAZINE
Mlochowski, Jacek,Szulc, Zdzislaw
, p. 33 - 39 (2007/10/02)
Formation and transformations of hydrazones, phenylhydrazones and azines, azafluorenone derivatives, have been studied and the influence of positions of heterocyclic nitrogen atoms on the reduction mechanism discussed.An improved reduction method of azafluorenones to azafluorenes has been elaborated.