245125-71-7

Basic information

• Product Name: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide
• Synonyms: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide
• CAS NO: 245125-71-7
• Molecular Weight: 436.517
• Mol File: 245125-71-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide(245125-71-7)
• EPA Substance Registry System: N,N,N',N'-tetraethyl-<2-(diphenylphosphino)phenyl>phosphonous acid diamide(245125-71-7)

Safety Data

• Hazardous Substances Data: 245125-71-7(Hazardous Substances Data)

Upstream product

• 583-53-9 2,3-dibromobenzene 
• 1079-66-9 chloro-diphenylphosphine 
• 685-83-6 bis(diethylamino)chlorophosphine 
• 62336-24-7 (2-bromophenyl)diphenylphosphane 

Downstream Products

• 223758-04-1 (R)-2-<2-(diphenylphosphino)phenyl>-1,3,2-dinaphtho1,2,f^1,2>dioxaphosphepine 
• 223742-01-6 <2-(diphenylphosphino)phenyl>phosphonous acid dichloride 

Relevant articles and documents

New non-C2-symmetric phosphine-phosphonites as ligands in asymmetric metal catalysis

Starting from 1,2-dibromobenzene, the synthesis of N,N,N',N'-tetraethyl-[2-(diphenylphosphino)phenyl]phosphonous acid tetraamide is possible in two simple steps. This key compound reacts with a variety of chiral diols such as (R)- and (S)-binaphthol, 1,2:5,6-diisopropylidene-D-mannitol or (1R,2R)-1,2-diphenyl-1,2-ethane diol to form the corresponding non-C2-symmetric phosphine-phosphonite compounds. These ligands react with Rh(COD)2BF4 to form bidentate Rh-complexes which serve as catalysts in the asymmetric hydrogenation of dimethyl itaconate with ee values of up to 88%.