245487-40-5 Usage
Chemical compound
1-cyclohexylpiperazine hydrochloride is a chemical compound commonly used in pharmaceutical research and drug development.
Derivative of piperazine
It is a derivative of piperazine, which gives it its unique chemical properties.
Interaction with receptors
1-cyclohexylpiperazine hydrochloride has the ability to interact with various receptors in the body, making it useful as a precursor in the creation of new pharmaceutical drugs.
Hydrochloride form
The compound is in hydrochloride form, which enhances its solubility and stability, making it more suitable for use in pharmaceutical applications.
Potential medical uses
1-cyclohexylpiperazine hydrochloride has been studied for its potential use in the treatment of various medical conditions, including neurological disorders and psychiatric illnesses.
Check Digit Verification of cas no
The CAS Registry Mumber 245487-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,5,4,8 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 245487-40:
(8*2)+(7*4)+(6*5)+(5*4)+(4*8)+(3*7)+(2*4)+(1*0)=155
155 % 10 = 5
So 245487-40-5 is a valid CAS Registry Number.
245487-40-5Relevant articles and documents
Preparation method of 1-cyclohexylpiperazine
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Paragraph 0028-0030, (2021/04/14)
The invention discloses a preparation method of 1-cyclohexylpiperazine. The method comprises the steps of carrying out reflux reaction on cyclohexyl halide, 1-Boc-piperazine and inorganic base in an organic solvent, filtering after the reaction is finished, and concentrating to obtain an intermediate 1; removing Boc from the intermediate 1 under an acidic condition, drying by distillation after the reaction is finished, pulping with isopropanol, and filtering to obtain solid 1-cyclohexyl piperazine hydrochloride; dissolving with water, adding an inorganic base to adjust the pH value to 12 to 14, extracting with an extraction solvent, drying the solvent by distillation to obtain a crude product of 1-cyclohexylpiperazine, and carrying out reduced pressure distillation on the crude product through an oil pump to obtain a pure product of 1-cyclohexylpiperazine. In the synthesis process of the intermediate 1, use of sodium triacetoxyborohydride and sodium hydroxide is avoided, the production cost is greatly saved, meanwhile, only filtering is needed for aftertreatment, the method is very simple, and time and labor are saved.
