24585-93-1

Basic information

• Product Name: 3-benzyl-6-chloroquinazolin-4(3H)-one
• Synonyms: 3-benzyl-6-chloroquinazolin-4(3H)-one
• CAS NO: 24585-93-1
• Molecular Weight: 270.718
• Mol File: 24585-93-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-benzyl-6-chloroquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-6-chloroquinazolin-4(3H)-one(24585-93-1)
• EPA Substance Registry System: 3-benzyl-6-chloroquinazolin-4(3H)-one(24585-93-1)

Safety Data

• Hazardous Substances Data: 24585-93-1(Hazardous Substances Data)

Upstream product

• 17422-32-1 5-chloro-1H-indole 
• 100-39-0 benzyl bromide 
• 16064-14-5 6-chloro-4-hydroxyquinazoline 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 635-21-2 5-chloroanthranilic acid 
• 100-46-9 benzylamine 

Downstream Products

• 7012-92-2 3-benzyl-6-chloro-2-phenylquinazolin-4(3H)-one 

Relevant articles and documents

Selective Oxidative Cleavage of 3-Methylindoles with Primary Amines Affording Quinazolinones

A selective functionalization of C-C-C bonds toward N-C-O bonds is realized by an n-Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique oxidant. The systematic process involves oxygenation, nitrogenation, ring-opening, and recyclization, affording a broad range of quinazolinones in good to excellent yields.

NMR studies of 3-substituted quinazolin-4(3H)-ones

3-Phenacyl-, 3-methylnaphthoyl-, 3-methylphenacyl- and 3-benzylquinazolin-4(3H)-one derivatives were synthesized and their 1H-NMR, 13C-NMR spectra were recorded. The chemical shifts and the coupling constants are reported.