24645-80-5 Usage
Description
P-Hydroxyphenylglyoxal monohydrate, with the molecular formula C8H8O4, is a monohydrate form of p-hydroxyphenylglyoxal. It is a phenylglyoxal derivative characterized by the presence of a phenolic group attached to the carbon chain. This white to off-white crystalline powder is soluble in both water and organic solvents. Due to its potential health hazards and environmental risks, it should be handled with care.
Uses
Used in Pharmaceutical Synthesis:
P-Hydroxyphenylglyoxal monohydrate is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a valuable component in the development of new drugs and fine chemicals.
Used in Agrochemical Production:
P-HYDROXYPHENYLGLYOXAL MONOHYDRATE also finds application in the production of agrochemicals, where it serves as an essential building block for the creation of effective and targeted agricultural products.
Used in Organic Synthesis:
P-Hydroxyphenylglyoxal monohydrate is employed in the field of organic synthesis, where it contributes to the development of a wide range of organic compounds for various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 24645-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,6,4 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 24645-80:
(7*2)+(6*4)+(5*6)+(4*4)+(3*5)+(2*8)+(1*0)=115
115 % 10 = 5
So 24645-80-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H6O3/c9-5-8(11)6-1-3-7(10)4-2-6/h1-5,10H
24645-80-5Relevant articles and documents
Coats et al.
, p. 131,134 (1976)
Structural elucidation, total synthesis, and cytotoxic activity of effphenol A
Chen, Shanchong,Chen, Yuchan,Dong, Chunmao,Liu, Hongxin,Liu, Zhaoming,Tan, Haibo,Zhang, Weimin,Zhang, Xiao
, p. 9035 - 9038 (2020/11/27)
A highly substituted phenol derivative, effphenol A (1), was isolated from the deep-sea-derived fungus Trichobotrys effuse FS524. Its complete structural assignment was established through a combination of spectroscopic analysis together with single-crystal X-ray diffraction experiments and further unequivocally confirmed by a biomimetic total synthesis. Structurally, effphenol A possesses a poly-substituted 6-5/6/6 tetracyclic ring system, which represents the first case of such a skeleton found in nature. Furthermore, the cytotoxic activity of effphenol A (1) toward four human cancer cell lines was assayed. This journal is
Design, synthesis and biological evaluation of 1-Phenyl-2-(phenylamino) Ethanone Derivatives as Novel MCR-1 Inhibitors
Lan, Xiu-juan,Yan, Hai-tao,Lin, Feng,Hou, Shi,Li, Chen-chen,Wang, Guang-shu,Sun, Wei,Xiao, Jun-hai,Li, Song
supporting information, (2019/08/07)
Polymyxins are considered to be the last-line antibiotics that are used to treat infections caused by multidrug-resistant (MDR) gram-negative bacteria; however, the plasmid-mediated transferable colistin resistance gene (mcr-1) has rendered polymyxins ine
