246852-12-0 Usage
General Description
Amlodipine mesylate is a pharmaceutical compound used for the treatment of high blood pressure and chest pain (angina). It belongs to the class of medications known as calcium channel blockers, which work by relaxing the blood vessels, allowing for easier blood flow and lowering blood pressure. Amlodipine mesylate specifically is a salt form of amlodipine, and it is often prescribed in combination with other antihypertensive medications. It has a long duration of action, with once-daily dosing, and is considered to be safe and effective in the management of hypertension and angina. However, like all medications, amlodipine mesylate may have potential side effects and interactions with other drugs, and should be taken as prescribed by a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 246852-12-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,6,8,5 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 246852-12:
(8*2)+(7*4)+(6*6)+(5*8)+(4*5)+(3*2)+(2*1)+(1*2)=150
150 % 10 = 0
So 246852-12-0 is a valid CAS Registry Number.
246852-12-0Relevant articles and documents
Amlodipine mesylate monohydrate as well as preparation method and application thereof
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Paragraph 0091-0092, (2021/03/24)
The invention relates to an amlodipine mesylate monohydrate as well as a preparation method and application thereof. The amlodipine mesylate monohydrate is a crystal, the particle size ranges of the crystal comprise: D10: 20-40 [mu]m, D50: 55-85 [mu]m and
ISOLATION OF DIHYDROPYRIDINE DERIVATIVE AND PREPARATION SALTS THEREOF
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Page 16, (2010/02/07)
The title compound is isolated in pure form by using a crystallization process and converted to its pharmaceutically acceptable salts. The crystallization process affects stability and purity of the amlodipine salts. All known impurities and one unknown impurity, which forms during the synthesis of the amlodipine salts, were isolated, characterized, and synthesized. A new method allowing the quantitative HPLC analysis of all related impurities of amlodipine salts in a single chromatogram was developed.