247233-68-7Relevant articles and documents
Structure-based design and synthesis of a novel class of Src SH2 inhibitors
Buchanan, John L.,Bohacek, Regine S.,Luke, George P.,Hatada, Marcos,Lu, Xiaode,Dalgarno, David C.,Narula, Surinder S.,Yuan, Ruth,Holt, Dennis A.
, p. 2353 - 2358 (2007/10/03)
The structure-based design and synthesis of a novel class of 2,4- disubstituted thiazoles as Src SH2 inhibitors is described. Initial results are presented, including the X-ray and NMR analysis of one thiazole inhibitor bound to Lck and Src SH2.
