24771-25-3

Basic information

• Product Name: DIMETHYL CYANOCARBONIMIDATE
• Synonyms: cyano-carbonimidicacidimethylester;cyano-dimidocarbonicacidimethylester;cyano-imidocarbonicacidimethylester;sk&f107533;DIMETHYL CYANOCARBONIMIDATE;DIMETHYL-N-CYANOIMIDOCARBONATE;CARBONIMIDIC ACID, CYANO-, DIMETHYL ESTER;dimethyl cyanoimidocarbonate
• CAS NO: 24771-25-3
• Molecular Formula: C₄H₆N₂O₂
• Molecular Weight: 114.1
• EINECS: 246-454-5
• Mol File: 24771-25-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 112.5°Cat760mmHg
• Flash Point: 21.8°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 21.7mmHg at 25°C
• Refractive Index: 1.431
• Solubility: DMSO; Methanol; Water
• CAS DataBase Reference: DIMETHYL CYANOCARBONIMIDATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL CYANOCARBONIMIDATE(24771-25-3)
• EPA Substance Registry System: DIMETHYL CYANOCARBONIMIDATE(24771-25-3)

Safety Data

• Hazardous Substances Data: 24771-25-3(Hazardous Substances Data)

Usage

Description

DIMETHYL CYANOCARBONIMIDATE, also known as Dimethyl (N-Cyanoimido)carbonate, is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its ability to react with other molecules, making it a versatile building block in the development of new drugs.

Uses

Used in Pharmaceutical Synthesis:
DIMETHYL CYANOCARBONIMIDATE is used as an intermediate in the synthesis of C988063, an impurity of Cimetidine (C441650). Cimetidine is a competitive histamine H2-receptor antagonist that inhibits gastric acid secretion and reduces pepsin output, making it useful in the treatment of conditions such as peptic ulcers and gastroesophageal reflux disease.
In the pharmaceutical industry, DIMETHYL CYANOCARBONIMIDATE plays a crucial role in the development of new drugs and the improvement of existing ones. Its reactivity and versatility make it a valuable compound for researchers and chemists working on drug synthesis and development.

InChI:InChI=1/C4H6N2O2/c1-7-4(8-2)6-3-5/h1-2H3

Upstream product

• 67-56-1 methanol 
• 10191-60-3 dimethyl N-cyanodithioiminocarbonate 
• 420-04-2 CYANAMID 
• 1850-14-2 tetramethoxymethane 
• 6263-27-0 Imidokohlensaeure-dimethylester 

Downstream Products

• 26364-65-8 2-(N-cyanoimino)thiazolidine 
• 31857-31-5 N¹,N²-dimethylcyanoguanidine 
• 795310-08-6 2-methoxy-6-amino-5,8-diaza-7,9-dicarbapurine 
• 26364-65-8 2-cyanoimino-1,3-thiazolidine 
• 1668-54-8 4-methoxy-6-methyl-1,3,5-triazin-2-amine 
• 82020-90-4 2-amino-4-isopropyl-6-methoxy-s-triazine 
• 26364-65-8 2-(cyanoimino)-thiazolidine 
• 146374-56-3 ethyl-(2-cyanoimino-5,6-dichloro-1,2,3,4-tetrahydroquinazolin-3-yl) acetate 

Relevant articles and documents

N-cyanogenetic imine a method for synthesis of diester carbonate

The invention discloses a synthesis method of N-cyanoimido bis carbonate. The method comprises the following steps: firstly, ensuring that carbon tetrachloride and alkali metal alcoholic compound are subjected to nucleophilic substitution, so as to produce dichloro dioxo alkyl methane, monochloro trioxide alkyl methane or tetroxide alkyl methane; secondly, preparation of N-cyanoimido bis carbonate crude products: ensuring that the dichloro dioxo alkyl methane is reacted with hydrogen cyanamide in alkaline condition, so as to produce N-cyanoimido bis carbonate and chloride, the monochloro trioxide alkyl methane is reacted with hydrogen cyanamide in alkaline condition, so as to produce N-cyanoimido bis carbonate and chloride, or the tetroxide alkyl methane is reacted with hydrogen cyanamide in alkaline condition, so as to produce N-cyanoimido bis carbonate; thirdly, refining of N-cyanoimido bis carbonate crude products. Compared with the existing production technology of N-cyanoimido bis carbonate, the method has the advantages that the adoption of highly toxic raw and supplemental materials, such as chlorine, cyanide and the like, is abandoned, and the method is simple to operate and environmentally friendly, and applicable to large-scale industrialized production.

FUNGICIDAL TRICYCLIC 1,2,4-TRIAZOLES

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, (I) wherein W is O, S(O)?n#191, NR5 or a direct bond; n is 0, 1 or 2; Q is O, S or NR6; G together with the two carbon atoms to which it is attached forms a 5 or 6-membered ring; and R1, R2, R3, R4, R5, and R6 are as defined in the Summary of the Invention. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

Mannich-type C-nucleosidations in the 5,8-diaza-7,9-dicarba-purine family

(Chemical Equation Presented) C-Nucleosidation with cyclic iminium salts occurring under mild reaction conditions and affording C-nucleosides that are isosteric with N-nucleosides of natural purines is shown to be a consistent property of the entire family of 2,6-(oxo or amino)-disubstituted 5,8-diaza-7,9-dicarba-purines.