2481-09-6

Basic information

• Product Name: S-tert-Butyl-L-cysteine hydrochloride
• Synonyms: H-CYS(BUT)-OH HCL;H-CYS(TBU)-OH HCL;H-CYS(TBU)-OH HYDROCHLORIDE;CYSTEINE(TBU)-OH HCL;S-T-BUTYL-L-CYSTEINE HCL;S-T-BUTYL-L-CYSTEINE HYDROCHLORIDE;S-T-BUTYL-L-CYSTEINE HYDROCHLORIDE SALT;S-TERT-BUTYL-L-CYSTEINE HYDROCHLORIDE
• CAS NO: 2481-09-6
• Molecular Formula: C₇H₁₅NO₂S*ClH
• Molecular Weight: 213.73
• Product Categories: Cysteine [Cys, C];Amino Acids and Derivatives;Amino hydrochloride;A - H;Amino Acids;Modified Amino Acids
• Mol File: 2481-09-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 203-204 °C
• Boiling Point: 293.5 °C at 760 mmHg
• Flash Point: 131.3 °C
• Appearance: White/Powder
• Density: 1.13g/cm3
• Vapor Pressure: 0.000421mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: 2-8°C
• CAS DataBase Reference: S-tert-Butyl-L-cysteine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: S-tert-Butyl-L-cysteine hydrochloride(2481-09-6)
• EPA Substance Registry System: S-tert-Butyl-L-cysteine hydrochloride(2481-09-6)

Safety Data

• Hazardous Substances Data: 2481-09-6(Hazardous Substances Data)

Usage

Description

S-tert-Butyl-L-cysteine hydrochloride is a protected form of L-Cysteine, a non-essential α-amino acid that is biosynthesized in humans. It plays a crucial role in various biological processes and has potential applications in different industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
S-tert-Butyl-L-cysteine hydrochloride is used as a precursor for the synthesis of various pharmaceutical compounds. Its role as a protected form of L-Cysteine allows for the development of drugs that can target specific biological pathways, making it a valuable component in drug discovery and design.
Used in Research and Development:
In the field of research and development, S-tert-Butyl-L-cysteine hydrochloride is used as a reagent for studying the properties and functions of L-Cysteine and its derivatives. This helps scientists understand the mechanisms of various biological processes and develop targeted therapies for various diseases.
Used in Nutraceutical Industry:
S-tert-Butyl-L-cysteine hydrochloride can be used as an additive in the nutraceutical industry, where it may contribute to the development of supplements and functional foods that promote health and well-being. Its role in the biosynthesis of L-Cysteine makes it a potential candidate for products aimed at supporting the immune system and overall health.
Used in Cosmetic Industry:
In the cosmetic industry, S-tert-Butyl-L-cysteine hydrochloride may be utilized for its antioxidant properties, which can help protect the skin from environmental stressors and promote a healthy, youthful appearance. It may also be used in the development of products that target specific skin concerns, such as aging or acne.
Used in Chemical Synthesis:
S-tert-Butyl-L-cysteine hydrochloride can be employed as a building block in the synthesis of various chemical compounds, including those with potential applications in materials science, electronics, and other industries. Its unique structure and properties make it a versatile component in the development of novel materials and technologies.

InChI:InChI=1/C7H15NO2S/c1-7(2,3)11-4-5(8)6(9)10/h5H,4,8H2,1-3H3,(H,9,10)/t5-/m0/s1

Upstream product

• 52-89-1 l-cysteine hydrochloride 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 15354-13-9 S-(2-nitrophenylsulfanyl)-L-cysteine 
• 56976-06-8 N-(Carbo-tert-butoxy)-S-tert-butyl-L-cysteine 
• 65798-34-7 Dicyclohexylamine Salt of N-<(2-Nitrophenyl)-sulfenyl>-S-tert-butyl-L-cysteine 
• 76499-09-7 -S-benzyl-L-cysteine Benzyl Ester 
• 76499-11-1 <-S-tert-butyl-L-cysteinyl>-L-phenylalanine tert-Butyl Ester 
• 76499-16-6 Bis<(S-tert-butyl-L-cysteinyl)-L-cystine> 
• 76499-08-6 (N-Formyl-S-tert-butyl-L-cysteinyl)-L-phenylalanine Methyl Ester 
• 76499-12-2 -L-phenylalanine 
• 76499-07-5 N-Tosyl-S-tert-butyl-L-cysteine Hydrazide 
• 76514-48-2 N-Tosyl-S-tert-butyl-L-cysteine Methyl Ester 
• 1002724-02-8 Boc-L-Cys(t-Bu)-OMe 
• 65798-32-5 N-Tosyl-S-tert-butyl-L-cysteine 
• 2481-12-1 Dicyclohexylamine Salt of N-(Carbobenzoxy)-S-tert-butyl-L-cysteine 
• 65798-33-6 N-<(2-Nitrophenyl)-sulfenyl>-S-tert-butyl-L-cysteine 

Relevant articles and documents

tert-Butyl group as thiol protection in peptide synthesis

S-tert-Butylcysteine was obtained by a new method. A number of its N-protected derivatives and esters were synthesized. Syntheses of several peptides containing tert-butyl and acetamidomethyl or benzyl thioethers of cysteine were carried out. The tert-butyl group was removed from the thiol group of peptides by treatment with (2-nitrophenyl)sulfenyl chloride (NpsCl). The S-(2-nitrophenyl)sulfenyl derivatives so obtained were converted either into cysteine by reduction or into cystine derivatives by disproportionation. Owing to the mild deprotection conditions and the great stability of the S-tert-butyl group, the other protecting groups, particularly those of the thiols, could be easily removed from a variety of combinations.