24860-46-6 Usage
General Description
2-Oxo-1-piperazineacetic acid is a chemical compound characterized by its organic nature. It falls into the class of compounds known as piperazines, which are compounds containing a piperazine ring, a six-membered ring with two nitrogen atoms and four carbon atoms. One of the key features of this chemical is the presence of a major functional group of carboxylic acids and 2-oxo compounds. 2-Oxo-1-piperazineacetic acid is less commonly known and not widely studied. It poses basic properties due to the presence of nitrogen in its structure, and the carboxylic group introduces acidic characteristics to this compound. It also exhibits complex reactivity due to the presence of both carboxylic and 2-oxo groups, offering a wide range of potential reactions and synthesis processes.
Check Digit Verification of cas no
The CAS Registry Mumber 24860-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,8,6 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 24860-46:
(7*2)+(6*4)+(5*8)+(4*6)+(3*0)+(2*4)+(1*6)=116
116 % 10 = 6
So 24860-46-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H10N2O3/c9-5-3-7-1-2-8(5)4-6(10)11/h7H,1-4H2,(H,10,11)
24860-46-6Relevant articles and documents
Design, synthesis, and structure-activity relationships of unsubstituted piperazinone-based transition state factor Xa inhibitors
Huang, Wenrong,Naughton, Mary Ann,Yang, Hua,Su, Ting,Dam, Suiko,Wong, Paul W.,Arfsten, Ann,Edwards, Susan,Sinha, Uma,Hollenbach, Stanley,Scarborough, Robert M.,Zhu, Bing-Yan
, p. 723 - 728 (2007/10/03)
A series of novel transition state factor Xa inhibitors containing a variety of lactam ring systems as central templates was synthesized in an expedient manner and allowed for a great deal of structural variability. Among them, the piperazinone-based inhibitors were found to be not only active against factor Xa but also selective over thrombin. Optimization of the P4 moiety yielded several potent compounds with IC50 below 1 nM against factor Xa.
