2491-17-0 Usage
Description
1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE, commonly known as CMC, is a reagent used in biochemistry and molecular biology. It is a white to slightly yellow powder with chemical properties that make it suitable for various applications in the field of biotechnology.
Uses
Used in Biochemistry and Molecular Biology:
1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE is used as a coupling agent for the formation of amide bonds between carboxylic acids and amines. It is particularly useful in the synthesis of peptides and other biomolecules, as it promotes efficient and specific coupling reactions.
Used in Facile Sequencing Technique:
In the field of RNA research, 1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE is employed in a facile sequencing technique for pseudouridylate residues in RNA. This application allows for the accurate identification and analysis of pseudouridine in RNA molecules, which is crucial for understanding RNA structure and function.
Used in Pharmaceutical Industry:
1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE is used as a reagent in the development of new drugs and drug candidates. Its ability to form stable amide bonds makes it a valuable tool in the synthesis of various pharmaceutical compounds, contributing to the advancement of drug discovery and development.
Used in Research and Development:
In academic and industrial research settings, 1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE is used as a key component in various biochemical and molecular biology experiments. Its versatility and efficiency in promoting amide bond formation make it an essential tool for researchers working with biomolecules and related applications.
Check Digit Verification of cas no
The CAS Registry Mumber 2491-17-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,9 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2491-17:
(6*2)+(5*4)+(4*9)+(3*1)+(2*1)+(1*7)=80
80 % 10 = 0
So 2491-17-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;
2491-17-0Relevant articles and documents
Preparation method of 1-cyclohexyl-2-(morpholinoethyl) carbodiimide methyl p-toluenesulfonate
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, (2021/05/08)
The invention provides a preparation method of 1-cyclohexyl-2-(morpholinoethyl) carbodiimide methyl p-toluenesulfonate, and the method comprises the following steps: S1, adding N-(2-aminoethyl) morpholine into a first organic solvent, and dropwise adding cyclohexyl isocyanate to generate an intermediate 1; S2, carrying out intramolecular dehydration reaction on the intermediate 1 to obtain an intermediate 2; S3, enabling the intermediate 2 to react with methyl p-toluenesulfonate, so as to generate the 1-cyclohexyl-2-(morpholinoethyl) carbodiimide methyl p-toluenesulfonate. According to the preparation method of the 1-cyclohexyl-2-(morpholinoethyl) carbodiimide methyl p-toluenesulfonate disclosed by the embodiment of the invention, a product with high purity can be smoothly obtained, and the method is good in operability, higher and stable in yield and easily available in raw materials.
Preparation of Carbodiimides Using Phase-Transfer Catalysis
Jaszay, Zsuzsa M.,Petnehazy, Imre,Toeke, Laszlo,Szajani, Bela
, p. 520 - 523 (2007/10/02)
A new method is described for the preparation of carbodiimides by dehydration of ureas with arenesulfonyl chlorides under solid-liquid phase-transfer catalytic (PTC) conditions using solid potassium carbonate as a base and a lipophilic quaternary ammonium salt as a catalyst.The method is generally applicable for the synthesis of disubstituted carbodiimides, but is especially useful for unsymmetrically substituted carbodiimides.The basic carbodiimides prepared were identified in the form of the more stable, crystalline quaternary salts.