25262-57-1

Basic information

• Product Name: Morpholine, 4-(3-phenylpropyl)-
• CAS NO: 25262-57-1
• Molecular Formula: C13H19NO
• Molecular Weight: 205.3
• Mol File: 25262-57-1.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-(3-phenylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(3-phenylpropyl)-(25262-57-1)
• EPA Substance Registry System: Morpholine, 4-(3-phenylpropyl)-(25262-57-1)

Safety Data

• Hazardous Substances Data: 25262-57-1(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 104-52-9 phenylpropyl chloride 
• 104-53-0 3-phenyl-propionaldehyde 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 3271-81-6 hydrocinnamanilide 
• 122-97-4 3-Phenyl-1-propanol 
• 104-54-1 3-Phenylpropenol 
• 16619-19-5 4-cinnamoylmorpholine 
• 103-67-3 benzyl-methyl-amine 
• 17077-46-2 4-(3-phenyl-propionyl)-morpholine 
• 645-45-4 hydrocinnamic acid chloride 
• 122-78-1 phenylacetaldehyde 
• 39655-59-9 4-(3-phenyl-1-propen-1-yl)-morpholine 

Relevant articles and documents

Mechanochemical Nucleophilic Substitution of Alcohols via Isouronium Intermediates**

An expansion of the solvent-free synthetic toolbox is essential for advances in the sustainable chemical industry. Mechanochemical reactions offer a superior safety profile and reduced amount of waste compared to conventional solvent-based synthesis. Here

B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines

A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is

Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes

The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst, dimethyl dicarbonate as an activator, and silane reductant effects this reduction for a wide variety of substrates, including pharmaceutically relevant structures, in good yields and with no overreduction to alcohols. Moreover, this methodology is scalable, allows access to deuterated aldehydes, and is also compatible with one-pot utilization of the aldehyde products.