253429-31-1

Basic information

• Product Name: 4-Fluoro-7-bromobenzofuran
• Synonyms: 4-Fluoro-7-bromobenzofuran;7-Bromo-4-fluorobenzo[b]furan;7-bromo-4-fluoro-1-benzofuran, 90%
• CAS NO: 253429-31-1
• Molecular Formula: C8H4BrFO
• Molecular Weight: 215.03
• Product Categories: Halides;Heterocycles
• Mol File: 253429-31-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 233℃
• Flash Point: 95℃
• Appearance: /
• Density: 1.696
• Vapor Pressure: 0.089mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Fluoro-7-bromobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoro-7-bromobenzofuran(253429-31-1)
• EPA Substance Registry System: 4-Fluoro-7-bromobenzofuran(253429-31-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 253429-31-1(Hazardous Substances Data)

Usage

General Description

4-Fluoro-7-bromobenzofuran is a chemical compound with the molecular formula C8H4BrFO. It is a derivative of benzofuran, containing a fluorine atom at the 4-position and a bromine atom at the 7-position. 4-Fluoro-7-bromobenzofuran is used in the field of organic chemistry as a building block for the synthesis of various pharmaceuticals and agrochemicals. It may also have potential applications in medicinal chemistry as a drug candidate due to its structural features and potential biological activities. However, its specific properties and uses have not been extensively studied or documented in scientific literature. Therefore, further research and investigation are required to fully understand the potential uses and applications of 4-Fluoro-7-bromobenzofuran.

InChI:InChI=1/C8H4BrFO/c9-6-1-2-7(10)5-3-4-11-8(5)6/h1-4H

Upstream product

• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 147460-41-1 2-bromo-5-fluorophenol 
• 664364-73-2 1-bromo-2-(2,2-dimethoxyethoxy)-4-fluorobenzene 
• 253429-18-4 2-(2-bromo-4-fluorophenol) acetaldehyde diethyl acetal 

Downstream Products

• 664364-74-3 4-fluoro-1-benzofuran-7-carbonitrile 
• 555155-07-2 4-fluorobenzofuran-7-carbaldehyde 
• 1037759-77-5 6-(5-carbamoyl-2-fluorobenzyl)-4-fluoro-8-(2-oxo-1,2-dihydropyridin-3-yl)-6H-furo[2,3-e]indole-7-carboxylic acid 

Relevant articles and documents

1,3-disubstituted ketene compound and application thereof

The invention relates to a 1,3-disubstituted ketene compound with a structure as shown in a formula (I) and application thereof. The compound mainly activates a PPAR (Peroxisome Proliferators-Activated Receptor) alpha, and also has excitation activity for PPPA delta and PPPA gamma. The 1,3-disubstituted ketene compound can be used for treating various diseases related to the PPAR regulation abnormality, such as NASH (nonalcoholic steatohepatitis), and particularly treating nonalcoholic hepatitis, also has potentials for treating diabetes, obesity, fibrotic diseases, cardiovascular diseases (comprising a heart failure, atherosclerosis and the like), kidney diseases (comprising chronic nephrosis, a kidney failure and the like), brain degenerative diseases (comprising the alzheimer disease and the like) and the like, and has higher application value. The formula is shown in the description.

TETRACYCLIC INDOLE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to Tetracyclic Indole Derivatives, compositions comprising at least one Tetracyclic Indole Derivative, and methods of using the Tetracyclic Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.

4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS

The present invention relates to 4,5-ring annulated indole derivatives, compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. Wherein ring Z, of formula (I), is a cyclopentyl, cyclopentenyl, 5-membered heterocycloalkyl, 5-membered heterocycloalkenyl or 5-membered heteroaryl ring.