253449-29-5

Basic information

• Product Name: ethyl N-<4-(2(S)-3-cyclohexyl-1-hydroxypropan-2-ylaminomethyl)-2-(2-methylphenyl)benzoyl>-L-methionine
• Synonyms: ethyl N-<4-(2(S)-3-cyclohexyl-1-hydroxypropan-2-ylaminomethyl)-2-(2-methylphenyl)benzoyl>-L-methionine
• CAS NO: 253449-29-5
• Molecular Weight: 540.767
• Mol File: 253449-29-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl N-<4-(2(S)-3-cyclohexyl-1-hydroxypropan-2-ylaminomethyl)-2-(2-methylphenyl)benzoyl>-L-methionine(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl N-<4-(2(S)-3-cyclohexyl-1-hydroxypropan-2-ylaminomethyl)-2-(2-methylphenyl)benzoyl>-L-methionine(253449-29-5)
• EPA Substance Registry System: ethyl N-<4-(2(S)-3-cyclohexyl-1-hydroxypropan-2-ylaminomethyl)-2-(2-methylphenyl)benzoyl>-L-methionine(253449-29-5)

Safety Data

• Hazardous Substances Data: 253449-29-5(Hazardous Substances Data)

Upstream product

• 253449-47-7 5-(hydroxymethyl)-2'-methyl(1,1'-biphenyl)-2-carboxylic Acid 
• 215919-30-5 methyl 5-(hydroxymethyl)-2'-methyl(1,1'-biphenyl)-2-carboxylate 
• 131288-67-0 (2S)-2-amino-3-cyclohexyl-1-propanol 
• 215919-23-6 ethyl N-<4-formyl-2-(2-methylphenyl)benzoyl>-L-methionine 

Relevant articles and documents

Discovery of a series of cyclohexylethylamine-containing protein farnesyltransferase inhibitors exhibiting potent cellular activity

Synthesis of a library of secondary benzylic amines based on the Sebti- Hamilton type peptidomimetic farnesyltransferase (FTase) inhibitor FTI-276 (1) led to the identification of 6 as a potent enzyme inhibitor (IC50 of 8 nM) which lacked the p