253594-42-2

Basic information

• Product Name: 3-iodo-6-(4-methoxy-phenylsulfanyl)-pyridazine
• Synonyms: 3-iodo-6-(4-methoxy-phenylsulfanyl)-pyridazine
• CAS NO: 253594-42-2
• Molecular Weight: 344.176
• Mol File: 253594-42-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-iodo-6-(4-methoxy-phenylsulfanyl)-pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-iodo-6-(4-methoxy-phenylsulfanyl)-pyridazine(253594-42-2)
• EPA Substance Registry System: 3-iodo-6-(4-methoxy-phenylsulfanyl)-pyridazine(253594-42-2)

Safety Data

• Hazardous Substances Data: 253594-42-2(Hazardous Substances Data)

Upstream product

• 696-63-9 4-Methoxybenzenethiol 
• 20698-04-8 3,6-diiodopyridazine 

Downstream Products

• 253594-45-5 C₁₁H₉IN₂O₃S 
• 253594-44-4 4-[6-[(4-methoxyphenyl)thio]-3-pyridazinylmethyl]-[1,4']-bipiperidinyl-1'-carboxylic acid, 1,1-dimethylethyl ester 
• 253594-43-3 1-piperidinecarboxylic acid, 4-[6-(4-methoxyphenyl)thio-3-pyridazinylmethyl],-1,1-dimethylethyl ester 

Relevant articles and documents

MUSCARINIC ANTAGONISTS

Heterocyclic derivatives of di-N-substituted piperazine or 1,4 di-substituted piperidine compounds in accordance with formula (I) (including all isomers, salts and solvates), wherein one of Y and Z is -N- and the other is -N- or -CH-; X is -O-, -S-, -SO-, -SO2- or -CH2-; Q is (1), (2), (3); R is alkyl, cycloalkyl, optionally substituted aryl or heteroaryl; R, R and R are H or alkyl; R is alkyl, cyclolalkyl or (4); R is H, alkyl, -C(O)alkyl, arylcarbonyl, -SO2alkyl, aryl-sulfonyl-C(O)Oalkyl, aryloxycarbonyl, -C(O)NH-alkyl or aryl-aminocarbonyl, wherein the aryl portion is optionally substituted; R is H or alkyl; and R is H, alkyl, hydroxyalkyl or alkoxyalkyl; are muscarinic antagonists useful for treating cognitive disorders such as Alzheimer's disease. Pharmaceutical compositions and methods of treatment are also disclosed.