25384-14-9 Usage
Description
2'-Aminoacetophenone hydrochloride is an organic compound that serves as an essential intermediate in the synthesis of various organic compounds, particularly in the production of α-benzamidoacetophenone and indazoles. It is a hydrochloride salt, which contributes to its reactivity and stability in chemical reactions.
Uses
Used in Pharmaceutical Industry:
2'-Aminoacetophenone hydrochloride is used as a key intermediate in the synthesis of α-benzamidoacetophenone, which is an important compound in the development of pharmaceuticals. This intermediate plays a crucial role in the production of various drugs, particularly those targeting specific medical conditions.
Used in Chemical Research:
In the field of chemical research, 2'-Aminoacetophenone hydrochloride is utilized as a building block for the synthesis of indazoles. Indazoles are a class of heterocyclic compounds that exhibit a wide range of biological activities and potential applications in medicinal chemistry. The synthesis of these compounds allows researchers to explore their properties and develop new therapeutic agents.
Overall, 2'-Aminoacetophenone hydrochloride is a versatile compound with significant applications in the pharmaceutical and chemical research industries, primarily due to its role in the synthesis of α-benzamidoacetophenone and indazoles. Its ability to participate in various chemical reactions makes it a valuable component in the development of new drugs and the advancement of scientific knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 25384-14-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,8 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25384-14:
(7*2)+(6*5)+(5*3)+(4*8)+(3*4)+(2*1)+(1*4)=109
109 % 10 = 9
So 25384-14-9 is a valid CAS Registry Number.
25384-14-9Relevant articles and documents
Selective and Additive-Free Hydrogenation of Nitroarenes Mediated by a DMSO-Tagged Molecular Cobalt Corrole Catalyst
Sch?fberger, Wolfgang,Timelthaler, Daniel,Topf, Christoph
supporting information, p. 2114 - 2120 (2021/07/22)
We report on the first cobalt corrole that effectively mediates the homogeneous hydrogenation of structurally diverse nitroarenes to afford the corresponding amines. The given catalyst is easily assembled prior to use from 4-tert-butylbenzaldehyde and pyrrole followed by metalation of the resulting corrole macrocycle with cobalt(II) acetate. The thus-prepared complex is self-contained in that the hydrogenation protocol is free from the requirement for adding any auxiliary reagent to elicit the catalytic activity of the applied metal complex. Moreover, a containment system is not required for the assembly of the hydrogenation reaction set-up as both the autoclave and the reaction vessels are readily charged under a regular laboratory atmosphere.
Steric Acceleration by Ortho Substituents of the Stannous Chloride Reduction of Nitrobenzenes in Aqueous Ethanol
Xing, Wen-Kan,Ogata, Yoshiro
, p. 3577 - 3581 (2007/10/02)
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