2547-61-7Relevant articles and documents
Sosnovsky
, p. 3506 (1961)
Preparation of 2-chloro-5-methyl-pyridine
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, (2008/06/13)
A process for the preparation of 2-chloro-5-methylpyridine of the formula STR1 which comprises reacting 3-methyl-pyridine-1-oxide of the formula STR2 with a chlorinating agent of the formula STR3 in which R1 represents alkyl, halogenoalkyl, cycloalkyl, optionally substituted aryl, NR2 R3 or OR4 in which R2 and R3 individually represent alkyl, cycloalkyl or aryl or together represent alkanediyl or oxaalkanediyl and R4 represents alkyl, cycloalkyl or optionally substituted aryl, in the presence of a basic organic nitrogen compound and in the presence of a diluent at a temperature between about -20° C. and +150° C.
Process for preparing amides by reaction in presence of molecular sieve
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, (2008/06/13)
There is provided a process for preparing amides which comprises reacting an amine, or an amide, and an acid halide, or anhydride, in suitable molecular proportions, in an inert organic diluent, in the presence of an effective amount of a molecular sieve, until the reaction is completed, separating the molecular sieve, and recovering the amide from the organic mother liquor.
Method of producing quaternary pyridinium compounds
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, (2008/06/13)
The method of preparing quaternary pyridinium compounds having the formula STR1 WHEREIN R represents alkyl, STR2 in which A is phenyl, naphthyl, carbostyrilyl, pyrazolinyl and substituted derivatives thereof where the substitutents are selected from the group consisting of alkyl having 1 to 4 carbon atoms, NO2, Cl, Br, phenyl, nitrophenyl and methylsulfonate; B is -O-alkylene-, STR3 AND C is selected from the group consisting of hydrogen, NHCOR1 and, when B is -O-alkylene, C can also be --OR2 -- where R1 is alkyl of 1 to 4 carbon atoms and R2 is alkylene of 1 to 4 carbon atoms; and wherein R4 represents lower alkyl having 1 to 6 carbon atoms, halophenyl, alkylphenyl or naphthyl, m represents an integer of 1 or 2 and m' is equal to m. The process for preparing the particularly designated compounds above comprises contacting pyridine and a hydroxy-containing compound having the formula: R'--(OH)n wherein R' represents alkyl, STR4 in which A' is phenyl, naphthyl, carbostyrilyl, pyrazolinyl and substituted derivatives thereof where the substituents are selected from the group consisting of alkyl having 1 to 4 carbon atoms, NO2, Cl, Br, phenyl, nitrophenyl and hydroxy; B, C, R1 and R2 are as defined above; and n is an integer of 1 or 2 and is equivalent to m defined above; reacting the pyridine and said hydroxy-containing compound in the presence of a sulfonyl halide having the formula R4 SO2 X wherein R4 is as defined above and X is Cl, Br or F; and conducting the reaction at an elevated temperature up to the reflux temperature of the reaction mixture. The quaternary pyridinium compounds can be used to prepare cationic surfactants, cationic pharmaceuticals, cationic dyestuffs, pesticides, fungicides and agricultural chemicals.
