25477-76-3

Basic information

• Product Name: 1,3-dimethyl-6-phenylpteridine-2,4(1H,3H)-dione
• CAS NO: 25477-76-3
• Molecular Formula: C₁₄H₁₂N₄O₂
• Molecular Weight: 268.2707
• Mol File: 25477-76-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 475°C at 760 mmHg
• Flash Point: 241.1°C
• Density: 1.32g/cm³
• Vapor Pressure: 3.45E-09mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 1,3-dimethyl-6-phenylpteridine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethyl-6-phenylpteridine-2,4(1H,3H)-dione(25477-76-3)
• EPA Substance Registry System: 1,3-dimethyl-6-phenylpteridine-2,4(1H,3H)-dione(25477-76-3)

Safety Data

• Hazardous Substances Data: 25477-76-3(Hazardous Substances Data)

Usage

Type of compound

Organic heterocyclic compound

Core structure

Pteridine

Attached group

Phenyl group

Biological activities

a. Precursor for the synthesis of folate
b. Involvement in DNA synthesis

Presence in natural products

Yes

Pharmaceutical industry applications

Potential applications

Studied for treatment of

Cancer, diabetes, and other diseases

Versatility

Diverse applications in biological and pharmaceutical fields

Upstream product

• 6632-68-4 6-amino-1,3-dimethyl-5-nitroso-1H-pyrimidine-2,4-dione 
• 122-78-1 phenylacetaldehyde 
• 50996-28-6 1,3-dimethyl-5-oxy-6-phenyl-1H-pteridine-2,4-dione 
• 6908-73-2 (E)-1-styrylpyrrolidine 
• 15030-41-8 3,6,8-trioxo-5,7-dimethyl-5,6,7,8-tetrahydro-3H-pyrimido<5,4-c><1,2,5>oxadiazine 
• 57044-58-3 (E)/(Z)-β-Trimethylsiloxystyrene 
• 14036-06-7 diethoxymethyl acetate 
• 5440-00-6 4,5-Diamino-1,3-dimethyluracil 
• 1074-12-0 phenylglyoxal hydrate 
• 60228-89-9 6-amino-1,3-dimethyl-5-{[1-phenylmeth-(E)-ylidene]-amino}-1H-pyrimidine-2,4-dione 
• 122-51-0 orthoformic acid triethyl ester 
• 50996-16-2 5,6-diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 101494-75-1 3-methylamino-6-phenyl-pyrazine-2-carboxylic acid methylamide 

Relevant articles and documents

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Synthesis, DNA binding and antiviral activity of new uracil, xanthine, and pteridine derivatives

Some new 6-amino-1,3-dimethyl-5-(substituted methylidene)aminouracils were synthesized. Most of them were cyclized with triethyl orthoformate as a one-carbon source to afford 1,3-dimethyl-6-substituted pteridine derivatives. Certain uracils gave xanthine

A novel method for introduction of carbon substituents into pteridine

A reaction of 1,3-dimethyl-6-trifluoromethanesulfonyloxylumazine with an anion of a 1,3-dicarbonyl compound such as diethyl malonate and 1,3- cyclohexanedione gives the corresponding 6-substituted lumazine.