2550-61-0 Usage
Description
Cesium methanesulfonate is a chemical compound that is utilized in the field of cell electrophysiology. It is characterized by its ability to act as a potassium (K+) channel blocker and its non-transportation through chloride (Cl-) channels.
Uses
Used in Cell Electrophysiology:
Cesium methanesulfonate is used as a current carrier for [application reason] its ability to block potassium (K+) channels and not be transported through chloride (Cl-) channels. This property makes it a valuable component in intracellular recording solutions of electrodes for patch clamp techniques, which are essential for studying the electrical properties of cells and their ion channels.
Used in Patch Clamp Recording System:
In the application industry of cell electrophysiology, cesium methanesulfonate is used as a supplement in intracellular solution for the patch clamp recording system. Its role in this system is to facilitate the study of ion channel activity and cell membrane potential, which are crucial for understanding various cellular processes and developing targeted therapies for a range of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 2550-61-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,5 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2550-61:
(6*2)+(5*5)+(4*5)+(3*0)+(2*6)+(1*1)=70
70 % 10 = 0
So 2550-61-0 is a valid CAS Registry Number.
InChI:InChI=1/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1/rCH3CsO3S/c1-6(3,4)5-2/h1H3
2550-61-0Relevant articles and documents
An Assessment of the Causes of the "Cesium Effect"
Dijkstra, Gerard,Kruizinga, Wim H.,Kellogg, Richard M.
, p. 4230 - 4234 (2007/10/02)
Cesium alkanoates (chiefly the propionate) have been investigated for their solubility, nucleophilic, reactivity and degree of ion pairing in dimethylformamide (DMF) and, in some cases, dimethyl sulfoxide (DMSO) solutions. 133Cs NMR has been used to establish the degree of ion pairing.From the data obtained it is concluded that the cesium ion is virtually completely solvated and that the carboxylates are essentially free and highly reactive.The consequences of this effect on macrocyclization by means of nucleophilic substitution are discussed.