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2564-05-8

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2564-05-8 Usage

Description

2-Chloro-N-(3-chlorophenyl)acetamide is an organic compound characterized by the presence of a chloroacetamide functional group attached to a chlorophenyl ring. This molecule is known for its potential applications in the chemical and pharmaceutical industries due to its unique structural features and reactivity.

Uses

Used in Chemical Synthesis:
2-Chloro-N-(3-chlorophenyl)acetamide is used as a key intermediate in the synthesis of novel substituted 2-chloroacetanalides. These compounds exhibit a wide range of chemical properties and can be further modified to create various derivatives with specific applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-chloro-N-(3-chlorophenyl)acetamide may be utilized as a building block for the development of new drugs with potential therapeutic applications. Its unique structure and reactivity can be exploited to design molecules with specific biological activities, such as antimicrobial, anti-inflammatory, or analgesic properties.
Used in Material Science:
The compound may also find applications in the field of material science, where it can be used to develop new materials with specific properties. For instance, it could be incorporated into the synthesis of polymers or other materials with tailored characteristics, such as improved mechanical strength, thermal stability, or chemical resistance.

Check Digit Verification of cas no

The CAS Registry Mumber 2564-05-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,6 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2564-05:
(6*2)+(5*5)+(4*6)+(3*4)+(2*0)+(1*5)=78
78 % 10 = 8
So 2564-05-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H7Cl2NO/c9-5-8(12)11-7-3-1-2-6(10)4-7/h1-4H,5H2,(H,11,12)

2564-05-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-CHLORO-N-(3-CHLOROPHENYL)ACETAMIDE

1.2 Other means of identification

Product number -
Other names 3-chloro-N-(chloroacetyl)aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2564-05-8 SDS

2564-05-8Relevant articles and documents

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy

Gangar, Mukesh,Goyal, Sandeep,Raykar, Digambar,Khurana, Princy,Martis, Ashwita M.,Goswami, Avijit,Ghoshal, Ishani,Patel, Ketul V.,Nagare, Yadav,Raikar, Santosh,Mukherjee, Apurba,Cyriac, Rajath,Paquin, Jean-Fran?ois,Kulkarni, Aditya

supporting information, (2021/12/20)

Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1 or NPP1), is an attractive therapeutic target for various diseases, primarily cancer and mineralization disorders. The ecto-enzyme is located on the cell surface and has been implicated in the control of extracellular levels of nucleotide, nucleoside and (di) phosphate. Recently, it has emerged as a critical phosphodiesterase that hydrolyzes cyclic 2′3′- cGAMP, the endogenous ligand for STING (STimulator of INterferon Genes). STING plays an important role in innate immunity by activating type I interferon in response to cytosolic 2′3′-cGAMP. ENPP1 negatively regulates the STING pathway and hence its inhibition makes it an attractive therapeutic target for cancer immunotherapy. Herein, we describe the design, optimization and biological evaluation studies of a series of novel non-nucleotidic thioguanine based small molecule inhibitors of ENPP1. The lead compound 43 has shown good in vitro potency, stability in SGF/SIF/PBS, selectivity, ADME properties and pharmacokinetic profile and finally potent anti-tumor response in vivo. These compounds are a good starting point for the development of potentially effective cancer immunotherapy agents.

Discovery of a Potent Botulinum Neurotoxin A Inhibitor ZM299 with Effective Protections in Botulism Mice

Gao, Jie,He, Zhili,Hong, Zhanying,Li, Tao,Luo, Deyan,Miao, Zhenyuan,Ning, Nianzhi,Wang, Hui,Wang, Jianxin,Wu, Yuelin,Xv, Xiguo,Zhang, Wannian,Zhang, Yanming,Zhuang, Chunlin

, p. 357 - 364 (2021/12/24)

Botulinum neurotoxins serotype A (BoNT/A) is the deadliest toxins known to humans and the "Category A" agent for bioterrorism. Over the past 20 years, significant efforts have been put forth to develop effective inhibitors of BoNT/A. Unfortunately, few id

Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2

Shin, Young Sup,Lee, Jun Young,Noh, Soojin,Kwak, Yoonna,Jeon, Sangeun,Kwon, Sunoh,Jin, Young-hee,Jang, Min Seong,Kim, Seungtaek,Song, Jong Hwan,Kim, Hyoung Rae,Park, Chul Min

supporting information, (2020/11/13)

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) continues to spread worldwide, with 25 million confirmed cases and 800 thousand deaths. Effective treatments to target SARS-CoV-2 are urgently needed. In the present study, we have identified a

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