2564-57-0

Basic information

• Product Name: 4-carbomethoxy-2-(4-methoxyphenyl)-δ²-thiazoline
• Synonyms: 4-carbomethoxy-2-(4-methoxyphenyl)-δ²-thiazoline
• CAS NO: 2564-57-0
• Molecular Weight: 251.306
• Mol File: 2564-57-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-carbomethoxy-2-(4-methoxyphenyl)-δ²-thiazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-carbomethoxy-2-(4-methoxyphenyl)-δ²-thiazoline(2564-57-0)
• EPA Substance Registry System: 4-carbomethoxy-2-(4-methoxyphenyl)-δ²-thiazoline(2564-57-0)

Safety Data

• Hazardous Substances Data: 2564-57-0(Hazardous Substances Data)

Upstream product

• 874-90-8 4-methoxybenzonitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 74-88-4 methyl iodide 
• 1492891-14-1 (R)-2-(4-methoxyphenyl)-4,5-dihydrothiazole-4-carboxylic acid 
• 309264-62-8 N-(4-methoxybenzoyl)-S-trityl-L-cysteine methyl ester 
• 18598-63-5 L-cysteine methyl ester hydrochloride 
• 95064-52-1 methyl 4-methoxybenzimidate 
• 2485-62-3 L-Cysteine methyl ester 
• 829-48-1 4-methoxy-benzimidic acid ethyl ester 
• 67-56-1 methanol 
• 52-90-4 L-Cysteine 
• 54998-29-7 ethyl 4-methoxybenzimidate hydrochloride 

Downstream Products

• 1370731-40-0 methyl 2-(p-methoxylphenyl)-5-phenylthiazole-4-carboxylate 
• 1315510-23-6 dimethyl 2,2'-di-(4-methoxylphenyl)-bis-5,5'-thiazole-4,4'-dicarboxylate 
• 1315510-08-7 methyl 2-(4-methoxylphenyl)thiazole-4-carboxylate 

Relevant articles and documents

Cu(i)-Catalyzed oxidative homo-coupling of thiazoline-4-carboxylates: Synthesis of 4,4′-bithiazoline derivatives

Cu(i)-Catalyzed oxidative homo-coupling of thiazoline-4-carboxylates with good functional group tolerance has been developed. The methodology presented an efficient method to directly construct vicinal carbon-hetero quaternary centers existing in numerous functional molecules and could be applied to the synthesis of 4,4′-bithiazoles which are difficult to prepare by direct C-H activation.

Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C-H bond cleavage

The first palladium-catalyzed direct C5-arylation of azole-4-carboxylates with simple unactivated arenes through double C-H bond cleavage is realized. This protocol provided a straightforward access to diverse 5-arylsubstituted azole-4-carboxylic derivatives with good functional group tolerance. The Royal Society of Chemistry 2012.

Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: Biomimetic syntheses of thiazoline- and thiazole-containing heterocycles

(matrix presented) The scope and limitations of TiCl4-mediated Δ2-thiazoline synthesis via tandem deprotection-dehydrocyclization of trityl-protected cysteine N-amides is presented. While chemical yields are acceptable (53-96%), the