25742-00-1

Basic information

• Product Name: 3-BROMO-5-HYDROXYMETHYLISOXAZOLE
• Synonyms: 3-BROMO-5-HYDROXYMETHYLISOXAZOLE;5-HYDROXYMETHYL-3-BROMOISOXAZOLE;(S)-2,3-Diaminopropanoic acid;(S)-2,3-Diaminopropanoic acid dihydrochloride;(3-Bromoisoxazol-5-yl)methanol;5-Isoxazolemethanol,3-bromo-;3-BroMo-5-isoxazoleMethanol;(3-broMo-1,2-oxazol-5-yl)Methanol
• CAS NO: 25742-00-1
• Molecular Formula: C4H4BrNO2
• Molecular Weight: 177.98
• Mol File: 25742-00-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 316.7°C at 760 mmHg
• Flash Point: 145.3°C
• Appearance: /
• Density: 1.864g/cm³
• Vapor Pressure: 0.00017mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.02±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-5-HYDROXYMETHYLISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-HYDROXYMETHYLISOXAZOLE(25742-00-1)
• EPA Substance Registry System: 3-BROMO-5-HYDROXYMETHYLISOXAZOLE(25742-00-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 25742-00-1(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-Hydroxymethylisoxazole is a chemical compound categorized under the isoxazole group, characterized by a five-membered heterocyclic ring, sharing similar properties with other organic compounds in the group. It contains three essential elements namely carbon, hydrogen and nitrogen, distinguished by its molecular combination of bromine and hydroxymethyl. Although detailed information on its applications or hazards is not widely documented, it is often involved in scientific research and laboratory synthesis. Like other laboratory chemicals, its handling may require adherence to safety and precautionary measures.

InChI:InChI=1/C4H4BrNO2/c5-4-1-3(2-7)8-6-4/h1,7H,2H2

Upstream product

• 74213-24-4 N-dibromomethylidenehydroxylamine 
• 51480-24-1 tetrahydropyranyloxypropargylmagnesium bromide 
• 107-19-7 propargyl alcohol 

Downstream Products

• 6567-35-7 3-bromo-5-isoxazolecarboxylic acid 
• 88982-28-9 3-bromo-5-(bromomethyl)isoxazole 
• 220780-57-4 3-bromo-isoxazole-5-carbaldehyde 

Relevant articles and documents

Synthesis of 5-(Fluoroalkyl)isoxazole Building Blocks by Regioselective Reactions of Functionalized Halogenoximes

A comprehensive study on the synthesis of 5-fluoroalkyl-substituted isoxazoles starting from functionalized halogenoximes is reported. One-pot metal-free [3 + 2] cycloaddition of CF3-substituted alkenes and halogenoximes bearing ester, bromo, c

BROMONITRILE OXIDE CYCLOADDITIONS IN WATER

Bromonitrile oxide can be generated homogeneously in water at acidic pH, allowing efficient cycloaddition with water soluble olefins and acetylenes.Allylammonium salts react with high regioselectivity and without the need for N-group protection. Keyword: Acivicin; transglutaminase; cysteine; 4,5-dihydroisoxazole; dibromonoformaldoxime.

1,3-Dipolar cycloaddition synthesis of 3-bromo-5-substituted isoxazoles, useful intermediates for the preparation of pharmacologically active compounds

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