25742-12-5

Basic information

• Product Name: 5-CYANOTHIAZOLE
• Synonyms: 5-CYANOTHIAZOLE;THIAZOLE-5-CARBONITRILE;5-Thiazolecarbonitrile;1,3-thiazole-5-carbonitrile
• CAS NO: 25742-12-5
• Molecular Formula: C4H2N2S
• Molecular Weight: 110.14
• Mol File: 25742-12-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 53 °C
• Boiling Point: 235.3°C at 760 mmHg
• Flash Point: 96.1°C
• Appearance: /
• Density: 1.33
• Vapor Pressure: 0.0505mmHg at 25°C
• Refractive Index: 1.574
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.40±0.10(Predicted)
• CAS DataBase Reference: 5-CYANOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CYANOTHIAZOLE(25742-12-5)
• EPA Substance Registry System: 5-CYANOTHIAZOLE(25742-12-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 25742-12-5(Hazardous Substances Data)

Usage

General Description

5-Cyanothiazole is a chemical compound with the molecular formula C4H3NSN. It is a heterocyclic compound that contains a five-membered ring with a nitrogen and sulfur atom. This chemical is used in the synthesis of pharmaceuticals and agrochemicals due to its ability to act as a building block in organic synthesis. 5-Cyanothiazole is also known for its potential use in the development of biologically active compounds and has been the subject of research for its antimicrobial, antiviral, and anticancer properties. 5-CYANOTHIAZOLE is important in the field of medicinal chemistry and is being investigated for its potential therapeutic applications.

InChI:InChI=1/C4H2N2S/c5-1-4-2-6-3-7-4/h2-3H

Upstream product

• 74411-19-1 thiazole-5-carboxamide 
• 107-14-2 chloroacetonitrile 
• 109-94-4 formic acid ethyl ester 
• 25850-66-2 4-Acetyl-5-cyan-thiazol 
• 3581-89-3 5-methylthiazole 
• 34241-39-9 azobisisobutyronitrile 
• 116045-57-9 1,3-thiazole-5-carbaldehyde oxime 
• 1003-32-3 thiazole-5-carboxaldehyde 

Downstream Products

• 91516-29-9 (1,3-thiazol-5-yl)(phenyl)methanone 
• 409110-07-2 thiazole-5-carbothioic acid amide 
• 52454-63-4 1,3-thiazol-5-ylacetic acid 

Relevant articles and documents

THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF

The present invention relates to a novel thienopyrimidine derivative and a use thereof, and more particularly, to a novel thienopyrimidine derivative compound and a composition for preventing or treating cancer comprising the same. The compound of the present invention can be effectively used for treating cancer with high FLT3 inhibitory activity and safety. In particular, the compound of the present invention has excellent solubility in physiological salt solutions including water, and thus can be more effectively used for development of therapeutic agents for cancer.COPYRIGHT KIPO 2018

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

Mycobacterial transcriptional repressor EthR controls the expression of EthA, the bacterial monooxygenase activating ethionamide, and is thus largely responsible for the low sensitivity of the human pathogen Mycobacterium tuberculosis to this antibiotic.