2577-62-0 Usage
Description
2,6-Diaminopimelic acid (DAP) is an organic compound that serves as an essential component in the biosynthesis of lysine, a crucial amino acid for various biological processes. It is a stereoisomer of meso-DAP and plays a significant role in the study and identification of bacteria and fungi in the rumen of ruminants.
Uses
Used in Pharmaceutical Industry:
2,6-Diaminopimelic acid is used as a reference material for the identification of bacterial and fungal markers in the rumen of ruminants. This application is crucial for understanding the microbial composition and its impact on the health and productivity of ruminant animals, such as cows and sheep.
Used in Research and Diagnostics:
In the field of research and diagnostics, 2,6-Diaminopimelic acid is utilized as a key component in assays and tests designed to detect and differentiate between various bacterial and fungal species present in the rumen. This helps in the development of targeted treatments and interventions to improve the overall health and well-being of ruminant animals.
Used in Microbiology:
2,6-Diaminopimelic acid is also used in microbiology as a tool for the classification and identification of bacteria and fungi. Its presence in certain species can provide valuable information about their taxonomy, ecological roles, and potential applications in various industries, such as agriculture and biotechnology.
Used in Ruminant Nutrition and Health:
In the context of ruminant nutrition and health, 2,6-Diaminopimelic acid plays a vital role in understanding the complex interactions between ruminant animals and their microbial populations. This knowledge can be applied to develop more effective feeding strategies, improve animal health, and enhance the sustainability of ruminant farming practices.
Biochem/physiol Actions
Stereoisomer of meso-DAP. meso-DAP is a biosynthetic precursor of the essential amino acid L-lysine and component of peptidoglycan in the cell wall of many bacteria. As these functions are not observed in mammalian biochemistry, alpha,alpha′-diamino diacids (DADs) are of interest as potential antibiotics with low mammalian toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 2577-62-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,7 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2577-62:
(6*2)+(5*5)+(4*7)+(3*7)+(2*6)+(1*2)=100
100 % 10 = 0
So 2577-62-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H14N2O4/c8-7(9,6(12)13)4-2-1-3-5(10)11/h1-4,8-9H2,(H,10,11)(H,12,13)
2577-62-0Relevant articles and documents
A simple chromatographic route for the isolation of meso diaminopimelic acid
Toth, Gabor K.,Hetenyi, Anasztazia,Ilisz, Istvan,Peter, Antal
experimental part, p. 133 - 137 (2011/11/05)
Meso diaminopimelic acid is an important noncoded amino acid found in Gram-negative bacterial peptidoglycan. In spite of its importance, this stereoisomer is not available commercially. A simple, economical procedure was developed for the isolation of pur
An efficient synthesis of (2S, 6S)- and meso-diaminopimelic acids via asymmetric hydrogenation
Wang,Xiong,Yang,Hruby
, p. 94 - 98 (2007/10/03)
An efficient synthesis of the title compounds 1 and 2 has been successfully developed. The key step is the asymmetric hydrogenation of dehydroamino acid 7 using [Rh(I)(COD)-(S,S) or - (R,R)-Et-DuPHOS)]+OTf- to produce the optically active, protected amino acid derivatives in high ee (>95%). The approach also can be used for the synthesis of other isomers and analogues.
A concise, stereoselective synthesis of meso-2,6-diaminopimelic acid (DAP)
Collier, Philip N.,Patel, Ian,Taylor, Richard J.K.
, p. 5953 - 5954 (2007/10/03)
The preparation of meso-2,6-diaminopimelic acid 1 is described. The key step in the synthesis is Suzuki coupling of the novel organoboron homoalanine equivalent 3 with methyl (2Z)-3-bromo-2-[(tert-butoxycarbonyl)amino]-2-propenoate 5.
