257938-68-4

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-, 1,1-dimethylethyl ester, (3R,4R)-
• CAS NO: 257938-68-4
• Molecular Formula: C27H37NO6
• Molecular Weight: 471.594
• Mol File: 257938-68-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-, 1,1-dimethylethyl ester, (3R,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-, 1,1-dimethylethyl ester, (3R,4R)-(257938-68-4)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-[3-[(2-methoxyphenyl)methoxy]propoxy]phenyl]-, 1,1-dimethylethyl ester, (3R,4R)-(257938-68-4)

Safety Data

• Hazardous Substances Data: 257938-68-4(Hazardous Substances Data)

Upstream product

• 188875-36-7 1-(3-Chloro-propoxymethyl)-2-methoxy-benzene 
• 257938-67-3 tert-butyl (3R,4R)-3-hydroxy-4-(4-hydroxyphenyl)-piperidine-1-carboxylate 
• 257938-64-0 (3R,4R)-4-(4-benzyloxy-phenyl)-1-((R)-1-phenyl-ethyl)-piperidin-3-ol 
• 257928-43-1 (R)-4-(4-benzyloxy-phenyl)-1-(1-phenyl-ethyl)-1,2,3,6-tetrahydro-pyridine 
• 783291-76-9 (3R,4R)-4-(4-Hydroxy-phenyl)-piperidin-3-ol 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 257938-72-0 (3R,4R)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-(quinolin-7-yl-methoxy)-piperidine-1-carboxylic acid tert-butyl ester 
• 257938-69-5 (3R,4R)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-[7-(2-trimethylsilanyl-ethoxymethoxy)-naphthalen-2-ylmethoxy]-piperidine-1-carboxylic acid tert-butylester 
• 857273-38-2 tert-butyl (3R,4R)-3-(1(S)-ethoxycarbonylethoxy)-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate 
• 304025-82-9 (3R,4R)-3-[1-(2-acetylamino-ethyl)-1,2,3,4-tetrahydro-quinolin-7-ylmethoxy]-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 304025-53-4 Ro 661168 
• 257938-73-1 (3R,4R)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-(1,2,3,4-tetrahydro-quinolin-7-ylmethoxy)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Piperidine renin inhibitors: from leads to drug candidates

Non-peptidomimetic renin inhibitors of the piperidine type represent a novel structural class of compounds potentially free of the drawbacks seen with peptidomimetic compounds so far. Synthetic optimization in two structural series focusing on improvement