25799-58-0

Basic information

• Product Name: H-D-Tyr(3-I)-OH
• Synonyms: H-D-Tyr(3-I)-OH
• CAS NO: 25799-58-0
• Molecular Formula: C₉H₁₀INO₃
• Molecular Weight: 307.08507
• Mol File: 25799-58-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 391.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.944±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.21±0.20(Predicted)
• CAS DataBase Reference: H-D-Tyr(3-I)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-Tyr(3-I)-OH(25799-58-0)
• EPA Substance Registry System: H-D-Tyr(3-I)-OH(25799-58-0)

Safety Data

• Hazardous Substances Data: 25799-58-0(Hazardous Substances Data)

Usage

General Description

H-D-Tyr(3-I)-OH is a chemical compound that contains the amino acid tyrosine with a hydroxyl group (OH) attached to the 3rd carbon atom, as well as a 3-iodine substituent. H-D-Tyr(3-I)-OH is a derivative of tyrosine and has potential applications in drug discovery and development. The 3-iodine modification can impact the compound's properties and interactions with biological targets, potentially enhancing its pharmacological effects. H-D-Tyr(3-I)-OH may be used in research and development of new pharmaceuticals, particularly in the field of neuroscience and oncology, where tyrosine derivatives have shown promise in targeting specific receptors and cellular pathways.

Upstream product

• 556-02-5 tyrosine 

Downstream Products

• 119336-08-2 methyl (R)-2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3-iodophenyl)propanoate 
• 119326-48-6 N-tert-butyloxycarbonyl-L-alanyl-N-methyl-D-3-iodotyrosyl-L-alanine methyl ester 
• 122908-63-8 N-tert-butyloxycarbonyl-N-methyl-O-t-butyldimethylsilyl-D-3-iodotyrosine methyl ester 
• 122886-24-2 3-iodo-N-methyl-D-tyrosine methyl ester 
• 122886-21-9 (R)-methyl 3-(4-((tert-butyldimethylsilyl)oxy)-3-iodophenyl)-2-(methylamino)propanoate 
• 122886-20-8 N-tert-butyloxycarbonyl-O-t-butyldimethylsilyl-D-3-iodotyrosine methyl ester 
• 122886-23-1 N-tert-butyloxycarbonyl-L-alanyl-N-methyl-D-3-iodotyrosine 
• 122886-22-0 N-tert-butyloxycarbonyl-L-alanyl-N-methyl-O-t-butyldimethylsilyl-D-3-iodotyrosine methyl ester 
• 119326-47-5 (S)-2-[(R)-3-(4-Hydroxy-3-iodo-phenyl)-2-methylamino-propionylamino]-propionic acid methyl ester 
• 119326-49-7 (S)-2-[(R)-2-[((S)-2-Amino-propionyl)-methyl-amino]-3-(4-hydroxy-3-iodo-phenyl)-propionylamino]-propionic acid methyl ester 
• 119326-53-3 (R)-2-tert-Butoxycarbonylamino-3-[3-iodo-4-(4-methoxy-benzyloxy)-phenyl]-propionic acid methyl ester 
• 119326-44-2 (R)-2-(tert-Butoxycarbonyl-methyl-amino)-3-[3-iodo-4-(4-methoxy-benzyloxy)-phenyl]-propionic acid methyl ester 
• 119326-46-4 (S)-2-{(R)-2-(tert-Butoxycarbonyl-methyl-amino)-3-[3-iodo-4-(4-methoxy-benzyloxy)-phenyl]-propionylamino}-propionic acid methyl ester 
• 108675-63-4 geodiamolide A 

Relevant articles and documents

Total Synthesis and Bioactivity Mapping of Geodiamolide H

The first total synthesis of the actin-stabilizing marine natural product geodiamolide H was achieved. Solid-phase based peptide assembly paired with scalable stereoselective syntheses of polyketide building blocks and an optimized esterification set the

Total Synthesis of Geodiamolide A, a Novel Cyclodepsipeptide of Marine Origin

Geodiamolide A (1), a cyclodepsipeptide isolated from the sponge Geodia containing the new amino acid (R)-3-iodo-N-methyltyrosine, was synthesized from its constituent tripeptide and 8-hydroxynonenoic acid subunits.Final closure of the 18-membered ring wa