25933-36-2 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 14 carbon (C) atoms, 9 hydrogen (H) atoms, 1 bromine (Br) atom, and 2 oxygen (O) atoms.
Explanation
This compound is a derivative of isobenzofuranone, which is a cyclic compound with a lactone group. The 4-bromophenyl group is attached to the isobenzofuranone structure, making it a brominated derivative.
Explanation
It is classified as an organic compound because it contains carbon and hydrogen atoms, along with other elements like bromine and oxygen.
Explanation
The compound has a lactone group, which is a cyclic ester, and a bromophenyl group, which is a phenyl group with a bromine atom attached.
Explanation
Due to its unique structure and properties, this compound may have potential applications in the fields of organic synthesis and pharmaceuticals, such as in the development of new drugs or chemical processes.
Explanation
As with any chemical compound, it is important to handle 1(3H)-Isobenzofuranone, 3-(4-bromophenyl)with care and follow appropriate safety protocols to minimize potential hazards associated with its use.
Explanation
The presence of the lactone and bromophenyl groups in the compound suggests that it may be reactive with various chemical species, such as nucleophiles and electrophiles, which could lead to further chemical reactions and modifications.
Explanation
Many organic compounds, especially those with functional groups like lactones and bromophenyl groups, can be sensitive to environmental factors such as light, heat, and moisture. This compound may require proper storage conditions to maintain its stability.
Explanation
Due to its nonpolar nature and the presence of carbon and hydrogen atoms, this compound is likely to be soluble in organic solvents such as dichloromethane, ethyl acetate, or acetone.
Explanation
The material provided does not include information about the melting or boiling points of this compound. These values are important for understanding the compound's physical properties and may be determined through experimental methods.
Structure
1(3H)-Isobenzofuranone, 3-(4-bromophenyl)-
Type
Organic compound
Functional groups
Lactone, Bromophenyl
Applications
Organic synthesis, Pharmaceuticals
Safety
Handle with care, follow safety protocols
Reactivity
Potential reactivity with nucleophiles, electrophiles, and other reactive species
Stability
May be sensitive to light, heat, and moisture
Solubility
Likely soluble in organic solvents
Melting Point/Boiling Point
Not provided
Check Digit Verification of cas no
The CAS Registry Mumber 25933-36-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,9,3 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 25933-36:
(7*2)+(6*5)+(5*9)+(4*3)+(3*3)+(2*3)+(1*6)=122
122 % 10 = 2
So 25933-36-2 is a valid CAS Registry Number.
25933-36-2Relevant articles and documents
Synthesis of chiral 3-substituted phthalides via rhodium(I)-catalyzed crossed alkyne cyclotrimerisation
Witulski, Bernhard,Zimmermann, Axel
, p. 1855 - 1859 (2002)
3-Substituted phthalides were synthesized for the first time by crossed alkyne cyclotrimerisations with Wilkinson's catalyst. Esterification of propiolic acids with chiral propargylic alcohols by either the DCC/DMAP or the Mitsunobu method allows the synt
Catalytic asymmetric synthesis of 3-aryl phthalides enabled by arylation-lactonization of 2-formylbenzoates
Carlos, Andressa M. M.,Stieler, Rafael,Lüdtke, Diogo S.
supporting information, p. 283 - 289 (2019/01/10)
The catalytic asymmetric synthesis of 3-aryl phthalides is reported through a sequential asymmetric arylation-lactonization reaction. The reaction is enabled by a boron-zinc exchange to generate reactive arylating agents, which react with 2-formylbenzoates in the presence of a chiral amino naphthol ligand. The enantiodetermining step is the arylation of the aldehyde, which then undergoes a lactonization event to yield the corresponding phthalides in good yields and enantioselectivities.
A concise synthesis of 3,4-fused spiro[isobenzofuran-3-ones], spiro[furo[3,4-b]pyridin-5(7H)-ones], 3-aryl-, and alkylphthalides
Kuethe, Jeffrey T.,Maloney, Kevin M.
, p. 5248 - 5258 (2013/06/27)
A synthetically useful protocol has been developed for the preparation of highly functionalized 3,4-fused spiro[isobenzofuran-3-ones], spiro[furo[3,4-b]pyridin-5(7H)-ones], 3-aryl-, and alkylphthalides. Reaction of 2-iodobenzoate esters and 2-iodopyridine carboxylate esters with i-PrMgCl·LiCl in the presence of cyclic ketones under standard Barbier reaction conditions affords 3,4-fused spiro[isobenzofuran-3-ones] and spiro[furo[3,4-b]pyridin-5(7H)-ones] in good to excellent yields. Step-wise addition of i-PrMgCl·LiCl to 2-iodobenzoate esters followed by trapping with various aldehydes yields 3-aryl and 3-alkylphthalides; whereas, under similar conditions access to 3-aryl and 3-alylazaphthalides is also possible. Extension of this methodology toward the preparation of 3-n-butylphthalide and chrycolide, a natural product isolated from the leaves and stems of Chrysanthemum coronarium, is also described.
