259858-34-9Relevant articles and documents
Indoline derivatives as 5-HT2C receptor agonists
Bentley,Adams,Bebbington,Benwell,Bickerdike,Davidson,Dawson,Dourish,Duncton,Gaur,George,Giles,Hamlyn,Kennett,Knight,Malcolm,Mansell,Misra,Monck,Pratt,Quirk,Roffey,Vickers,Cliffe
, p. 2367 - 2370 (2004)
A series of 1-(1-indolinyl)-2-propylamines was synthesised and evaluated as 5-HT2C receptor agonists for the treatment of obesity. The general methods of synthesis of the precursor indoles are described. The functional efficacy and radioligand