2613-89-0

Basic information

• Product Name: Phenylmalonic acid
• Synonyms: PHENYLPROPANEDIOC ACID;PHENYLMALONIC ACID;RARECHEM AL BE 1370;phenyl-propanedioicaci;1-Hydroxy-4-(P-Tolyamino)Anthraquinone;alpha-Carboxyphenylaceticacid;Phenylpropanedionicacid;PHENYLPROPANEDIOIC ACID
• CAS NO: 2613-89-0
• Molecular Formula: C₉H₈O₄
• Molecular Weight: 180.16
• EINECS: 220-044-6
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acid Monomers;Monomers;Polymer Science
• Mol File: 2613-89-0.mol
• Article Data: 16

Chemical Properties

• Melting Point: 149-152 °C (dec.)(lit.)
• Boiling Point: 272.96°C (rough estimate)
• Flash Point: 187.5 °C
• Appearance: white to off-white crystalline powder
• Density: 1.2933 (rough estimate)
• Vapor Pressure: 6.63E-06mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: pK1:2.58;pK2:5.03 (25°C)
• Water Solubility: soluble
• BRN: 2048729
• CAS DataBase Reference: Phenylmalonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylmalonic acid(2613-89-0)
• EPA Substance Registry System: Phenylmalonic acid(2613-89-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-22
• Safety Statements: 26-36-24/25
• WGK Germany: 3
• Hazardous Substances Data: 2613-89-0(Hazardous Substances Data)

Usage

Description

Phenylmalonic acid is a white to off-white crystalline powder with chemical properties that make it a valuable starting material in the synthesis of various compounds.

Uses

Used in Pharmaceutical Industry:
Phenylmalonic acid is used as a starting material for the synthesis of Sodium Indanylcarbinicillin (S635000), a compound that has demonstrated the ability to reduce blood pressure in mammals. Additionally, Sodium Indanylcarbinicillin has been utilized as a β-lactam antibiotic, highlighting the importance of Phenylmalonic acid in the development of pharmaceuticals for treating hypertension and bacterial infections.

InChI:InChI=1/C9H8O4/c10-8(11)7(9(12)13)6-4-2-1-3-5-6/h1-5,7H,(H,10,11)(H,12,13)/p-2

Upstream product

• 103-82-2 phenylacetic acid 
• 37434-59-6 dimethyl 2-phenylmalonate 
• 83-13-6 diethyl 2-phenylmalonate 
• 108-88-3 toluene 
• 1623-99-0 phenyl sodium 
• 71-43-2 benzene 
• 1807-69-8 2-diazo-3-oxo-3-phenyl-propionic acid methyl ester 
• 98-87-3 benzylidene dichloride 
• 124-38-9 carbon dioxide 
• 20279-16-7 3-hydroxydibenzofuran 
• 60-29-7 diethyl ether 
• 111-65-9 octane 
• 1822-71-5 n-pentylsodium 
• 114-70-5 sodium phenylacetate 

Downstream Products

• 37434-59-6 dimethyl 2-phenylmalonate 
• 4370-95-0 3-amino-2-phenyl-propionic acid 
• 7391-66-4 1,3-dimethyl-5-phenyl-pyrimidine-2,4,6(1H,3H,5H)-trione 
• 103-82-2 phenylacetic acid 
• 15231-78-4 2.2-dimethyl-5-phenyl-1,3-dioxane-4,6-dione 
• 37818-48-7 2-Phenyl-propanedioyl dichloride 
• 112081-08-0 chloro-phenyl-malonyl chloride 
• 70882-17-6 bromophenylmalonic acid 
• 2835-06-5 phenylglycin 
• 112116-87-7 phenyl-malonic acid di-m-tolyl ester 
• 6286-14-2 3-dimethylamino-2-phenyl-propionic acid 
• 855183-94-7 N,N'-phenylmalonyl-bis-carbamic acid diethyl ester 
• 3426-01-5 1,4-diphenyl-pyrazolidine-3,5-dione 
• 7138-86-5 3-morpholin-4-yl-2-phenyl-propionic acid 

Relevant articles and documents

Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide

A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent cou

Mesoionic insecticide

The invention relates to a mesoionic compound. Specifically, the present invention relates to a mesoionic compound represented by formula (I) or a stereoisomer, a nitrogen oxide and a salt thereof ofthe mesoionic compound represented by formula (I), and a process for the preparation of mesoionic compounds, and their use as insecticides in agriculture, and their forms of insecticide compositions,as well as methods of controlling pests with these compounds or compositions; wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, n, R6 and R7 have the meanings described in the invention.

Kinetics and Mechanism of Oxidation of Carbenicillin by Copper (III) Periodate Complex in Aqueous Alkaline Medium

Kinetics and mechanism of oxidation of carbenicillin by diperiodatocuprate [DPC-III] in aqueous alkaline medium were studied spectrophotometrically at 298 K and an ionic strength of 0.10 mol·dm-3. The reaction between DPC (III) and carbenicilli