26301-79-1 Usage
Description
D-Mannono-1,4-lactone is a white solid that is an isomer of D-lyono-1,4-lactone and is derived from the oxidation of D-mannose. It is known for its ability to inhibit the β-galactosidase enzyme of Escherichia coli, with its furanose form playing a significant role in its efficacy.
Uses
Used in Pharmaceutical Industry:
D-Mannono-1,4-lactone is used as an enzyme inhibitor for β-galactosidase in Escherichia coli, which is important for studying the enzyme's function and developing potential therapeutic agents targeting this enzyme.
Used in Chemical Research:
As a white solid with unique chemical properties, D-Mannono-1,4-lactone can be utilized in various chemical research applications, including the study of sugar derivatives, enzyme inhibition mechanisms, and the development of new synthetic pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 26301-79-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,3,0 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 26301-79:
(7*2)+(6*6)+(5*3)+(4*0)+(3*1)+(2*7)+(1*9)=91
91 % 10 = 1
So 26301-79-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1
26301-79-1Relevant articles and documents
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Isbell
, p. 2166 (1933)
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Facile syntheses of 1-deoxynojirimycin (DNJ) and 1-deoxymannojirimycin (DMJ)
Song, Xuezheng,Hollingsworth, Rawle I.
, p. 3115 - 3118 (2007)
1-Deoxynojirimycin (DNJ) and 1-deoxymannojirimycin (DMJ) were synthesized through a concise and practicable pathway. A strategy of using carbohydrate derivatives bearing two leaving groups in the preparation of azasugars by di-N-alkylation of amines was developed. The strategy involved the selective partial protection of dibromo alditols.
Syntheses of (3R,4R,5R,6R)-tetrahydroxyazepane (1,6-dideoxy-1,6-imino-D-mannitol) and (3S,4R,5R,6R)-tetrahydroxyazepane (1,6-dideoxy-1,6-imino-D-glucitol)
Joseph, Cosam C,Regeling, Henk,Zwanenburg, Binne,Chittenden, Gordon J.F
, p. 6907 - 6911 (2007/10/03)
Syntheses of 1,6-dideoxy-1,6-imino-D-mannitol (D-mannoazepane) (1) and 1,6-dideoxy-1,6-imino-D-glucitol (D-glucoazepane) (3) from D-isoascorbic acid and D-glucono-1,5-lactone, respectively, are described. The key step in both routes involved reductive aminative 1,6-cyclization with retention of configurations to give the corresponding lactams, which were subsequently reduced to afford compounds 1 and 3 in 24 and 28.5%, overall yield, respectively.