267899-36-5Relevant articles and documents
A one-pot three-component reaction for the preparation of highly functionalized tryptamines
Yeo, Se Jeong,Liu, Yongxiang,Wang, Xiang
supporting information; experimental part, p. 813 - 818 (2012/02/01)
We have developed a general one-pot method to provide highly functionalized tryptamine derivatives, via a Fischer indole type pathway. In this article, we demonstrate optimal conditions for a one-pot indole synthesis, allowing for the synthesis of a broad scope of 2-methyl tryptamine derivatives and a precursor for the synthesis of the core structure of some akuammiline alkaloids. Additionally, further modification of the indole products is described.
