26820-31-5 Usage
Description
2-[(4-CHLOROPHENYL)THIO]-3-NITROPYRIDINE is a chemical compound with the molecular formula C11H7ClN2OS. It is a synthetic intermediate used in the pharmaceutical industry for the preparation of various drugs and agrochemicals. 2-[(4-CHLOROPHENYL)THIO]-3-NITROPYRIDINE features a pyridine ring with a nitro group at the 3-position and a thioether group attached to the 2-position, which is substituted with a 4-chlorophenyl group. The nitro group endows the compound with reactivity, making it useful in organic synthesis, while the 4-chlorophenyl group provides a specific functional group for further transformations. 2-[(4-CHLOROPHENYL)THIO]-3-NITROPYRIDINE plays a significant role in the development of various therapeutic agents and agricultural chemicals.
Uses
Used in Pharmaceutical Industry:
2-[(4-CHLOROPHENYL)THIO]-3-NITROPYRIDINE is used as a synthetic intermediate for the preparation of various drugs. Its unique structure allows for the development of therapeutic agents with specific functionalities and properties.
Used in Agrochemical Industry:
2-[(4-CHLOROPHENYL)THIO]-3-NITROPYRIDINE is also used as a synthetic intermediate for the preparation of agrochemicals. Its reactivity and specific functional groups make it a valuable component in the creation of agricultural chemicals designed to protect crops and enhance yields.
Check Digit Verification of cas no
The CAS Registry Mumber 26820-31-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,8,2 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 26820-31:
(7*2)+(6*6)+(5*8)+(4*2)+(3*0)+(2*3)+(1*1)=105
105 % 10 = 5
So 26820-31-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H7ClN2O2S/c12-8-3-5-9(6-4-8)17-11-10(14(15)16)2-1-7-13-11/h1-7H
26820-31-5Relevant articles and documents
Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach
Xiang, Jinbao,Zhang, Zhuoqi,Mu, Yan,Xu, Xianxiu,Guo, Sigen,Liu, Yongjin,Russo, Daniel P.,Zhu, Hao,Yan, Bing,Bai, Xu
supporting information, p. 230 - 235 (2016/06/01)
An efficient discovery strategy by combining diversity-oriented synthesis and converging cellular screening is described. By a three-round screening process, we identified novel tricyclic pyrido[2,3-b][1,4]benzothiazepines showing potent inhibitory activity against paclitaxel-resistant cell line H460TaxR (EC50 50 > 100 μM against normal human fibroblasts). The most active hits also exhibited drug-like properties suitable for further preclinical research. This redeployment of antidepressing compounds for anticancer applications provides promising future prospects for treating drug-resistant tumors with fewer side effects.
