268733-98-8

Basic information

• Product Name: 4-bromophenyl 4,4-dimethylpentanoate
• Synonyms: 4-bromophenyl 4,4-dimethylpentanoate
• CAS NO: 268733-98-8
• Molecular Weight: 285.181
• Mol File: 268733-98-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-bromophenyl 4,4-dimethylpentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromophenyl 4,4-dimethylpentanoate(268733-98-8)
• EPA Substance Registry System: 4-bromophenyl 4,4-dimethylpentanoate(268733-98-8)

Safety Data

• Hazardous Substances Data: 268733-98-8(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 507-20-0 tertiary butyl chloride 
• 50663-21-3 (para-bromophenyl)-2-propenoate 
• 624-95-3 3,3-dimethylbutanol 
• 1647-23-0 3,3-dimethylbutyl bromide 
• 1118-47-4 4,4-dimethylpentanoic acid 

Relevant articles and documents

Ti-Catalyzed Radical Alkylation of Secondary and Tertiary Alkyl Chlorides Using Michael Acceptors

Alkyl chlorides are common functional groups in synthetic organic chemistry. However, the engagement of unactivated alkyl chlorides, especially tertiary alkyl chlorides, in transition-metal-catalyzed C-C bond formation remains challenging. Herein, we describe the development of a TiIII-catalyzed radical addition of 2° and 3° alkyl chlorides to electron-deficient alkenes. Mechanistic data are consistent with inner-sphere activation of the C-Cl bond featuring TiIII-mediated Cl atom abstraction. Evidence suggests that the active TiIII catalyst is generated from the TiIV precursor in a Lewis-acid-assisted electron transfer process.