270078-95-0

Basic information

• Product Name: (R,R)-N,N'-bis(1-diphenylmethyl-2-hydroxyethyl)oxamide
• Synonyms: (R,R)-N,N'-bis(1-diphenylmethyl-2-hydroxyethyl)oxamide
• CAS NO: 270078-95-0
• Molecular Weight: 508.617
• Mol File: 270078-95-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,R)-N,N'-bis(1-diphenylmethyl-2-hydroxyethyl)oxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R)-N,N'-bis(1-diphenylmethyl-2-hydroxyethyl)oxamide(270078-95-0)
• EPA Substance Registry System: (R,R)-N,N'-bis(1-diphenylmethyl-2-hydroxyethyl)oxamide(270078-95-0)

Safety Data

• Hazardous Substances Data: 270078-95-0(Hazardous Substances Data)

Upstream product

• 553-90-2 Dimethyl oxalate 
• 171037-01-7 (R)-2-amino-3,3-diphenyl-1-propanol 

Downstream Products

• 270078-96-1 (R,R)-N,N'-bis[2-chloro-1-(diphenylmethyl)ethyl]oxamide 

Relevant articles and documents

Bisoxazoline and bioxazoline chiral ligands bearing 4-diphenylmethyl shielding substituents. Diels-Alder reaction of cyclopentadiene with 3-acryloyl-2-oxazolidinone catalyzed by the aqua nickel(II) complex

Enantiopure 2-amino-3,3-diphenyl-1-propanol was synthesized by the hidantoin route starting from diphenyl-acetaldehyde followed by subsequent functional group transformations and optical resolution by a chiral HPLC. The amino alcohol can be converted into two new chiral ligands: 4,4'-bis(diphenylmethyl)-2,2'-bioxazoline and 2,2'-isopropylidenebis(4-diphenylmethyloxazoline), and further to complexes with copper(II) trifluoromethanesulfonate and nickel(II) perchlorate hexahydrate. The nickel(II) aqua complex obtained from the bisoxazoline effectively catalyzed the Diels-Alder reactions of cyclopentadiene with 3-acryloyl-2-oxazolidinone in high endo-selectivities and moderate enantioselectivities via a square planar transition structure.