270575-75-2Relevant articles and documents
Solid phase synthesis of oligoureas using O-succinimidyl-(9H-fluoren-9- ylmethoxycarbonylamino)ethylcarbamate derivatives as activated monomers
Guichard, Gilles,Semetey, Vincent,Rodriguez, Marc,Briand, Jean-Paul
, p. 1553 - 1557 (2000)
An efficient stepwise synthesis of oligoureas (up to the nonamer) on solid support using O-succinimidyl-(9H-fluoren-9- ylmethoxycarbonylamino)ethylcarbamate derivatives as activated monomers is described. These building blocks were readily prepared starting from N-Fmoc- protected β3-amino acids via Curtius rearrangement of the corresponding acyl azides and treatment of the resulting isocyanate with N- hydroxysuccinimide. (C) 2000 Elsevier Science Ltd.