270902-48-2

Basic information

• Product Name: OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE
• Synonyms: OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE;Cyclopenta[c]pyrrole-1-carboxylic acid, octahydro- (9CI);Cyclopenta[c]pyrrole-1-carboxylic acid, octahydro-
• CAS NO: 270902-48-2
• Molecular Formula: C8H13NO2
• Molecular Weight: 155.19432
• Product Categories: CARBOXYLICACID;PYRROLE;GLYCINESCAFFOLD
• Mol File: 270902-48-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE(270902-48-2)
• EPA Substance Registry System: OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE(270902-48-2)

Safety Data

• Hazardous Substances Data: 270902-48-2(Hazardous Substances Data)

Usage

General Description

OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE is a chemical compound that belongs to the class of pyrrolidine derivatives. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE is a white to off-white solid that is soluble in water and has a molecular weight of 227.71 g/mol. Its hydrochloride form is commonly used in pharmaceutical formulations due to its increased stability and improved solubility. OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID HYDROCHLORIDE has applications in the development of anti-cancer drugs, central nervous system agents, and cardiovascular medications. It is important to handle and store this chemical compound in accordance with safety guidelines to prevent any potential hazards.

InChI:InChI=1/C8H13NO2.ClH/c10-8(11)7-6-3-1-2-5(6)4-9-7;/h5-7,9H,1-4H2,(H,10,11);1H

Upstream product

• 1037834-39-1 (3aR,6aS)-octahydrocyclopenta[c]pyrrole 
• 926276-09-7 C₁₃H₂₁NO₄ 
• 1205676-37-4 (1S,3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carbonitrile 
• 1414976-24-1 C₉H₁₇NO₂ 
• 1414976-28-5 C₁₆H₂₃NO₂ 
• 1414976-36-5 C₁₅H₁₉NO₂ 
• 6140-65-4 1-cyclopentene-1-carboxaldehyde 
• 1414976-22-9 C₉H₁₅NO₄ 
• 629-11-8 1,6-hexanediol 
• 1292320-79-6 (1R,2R)-2-(nitromethyl)cyclopentane-1-carbaldehyde 
• 1227703-21-0 (3aR,6aS)-1,3a,4,5,6,6a-hexahydrocyclopenta[c]pyrrole 
• 1227703-50-5 octahydrocyclopenta[c]pyrrole-1-carbonitrile 
• 55489-11-7 6,6-dimethoxyhexanal 
• 110-83-8 cyclohexene 

Relevant articles and documents

Unraveling the C2-Symmetric Azatetraquinane System. Simple, Enantioselective Syntheses

Concise stereocontrolled synthetic routes to the C2-symmetric azatetraquinane 1 (or, also, the enantiomer) are described. The successful execution of the synthesis involved innovation in the methodology for [3+2] cycloaddition and stereochemical control.

An Improved and Enantioselective Preparation of the Telaprevir Bicyclic [3.3.0] Proline Intermediate and Reuse of Unwanted Enantiomer

An improved, concise, and efficient preparation of the telaprevir bicyclic [3.3.0] proline intermediate is presented. The key steps, control points, and the whole process are optimized. The synthesis of racemic intermediate was accomplished in five steps

PROCESS FOR PRODUCING ESTER COMPOUND

Compound (1) or a salt that is useful as an intermediate for the production of a medicine, an agrochemical or the like can be produced by a process including the following steps: (A) reacting an aldehyde (2) with nitromethane to produce a nitroaldehyde; (B) reacting the nitroaldehyde with an alcohol to produce a nitroacetal; (C) reducing the nitroacetal to produce an aminoacetal; (D) protecting an amino group in the aminoacetal to produce a protected aminoacetal; (E) treating the protected aminoacetal with an acid and subsequently with a base and then reacting the resultant product with a cyanating agent to produce a nitrile; (F) hydrolyzing the nitrile to produce a protected amino acid; and (G) substituting a group R5 in the protected amino acid by a hydrogen atom and protecting a carboxyl group therein.