27093-39-6

Basic information

• Product Name: benzyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylate
• Synonyms: benzyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylate
• CAS NO: 27093-39-6
• Molecular Weight: 243.305
• Mol File: 27093-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylate(27093-39-6)
• EPA Substance Registry System: benzyl 2,4,5-trimethyl-1H-pyrrole-3-carboxylate(27093-39-6)

Safety Data

• Hazardous Substances Data: 27093-39-6(Hazardous Substances Data)

Upstream product

• 55536-73-7 2,4,6-trimethyl-pyridine-3,5-dicarboxylic acid dibenzyl ester 
• 5396-89-4 benzyl acetoacetate 
• 135636-66-7 butane-2,3-dione mono-oxime 

Relevant articles and documents

Ring-contraction of hantzsch esters and their derivatives to pyrrolesviaelectrochemical extrusion of ethyl acetate out of aromatic rings

Electrochemical ring-contraction of HEs and theirs pyridine derivatives is developed to obtain polysubstituted pyrroles. This process provides an orthogonal utilization of Hantzsch esters for the well-documented application as side chain or hydrogen donors. The formal transformation shows an extrusion of ethyl acetate out of the pyridine ring in a single step. In addition to the novel transformation, we also discovered the Lewis acid's intermolecular control of regioselectivity during an intramolecular electrochemical process. The reaction provides a number of polysubstituted pyrroles that have never been accessed, including pharmaceutical intermediates and photoswitches. An unusual 4-electron continuous reduction drives the unprecedented anionic dearomatization/ring-contraction/rearomatization pathway.